首页> 外国专利> ACCUMULATIVE BORON 10 MEDICINE FOR BORON NEUTRON CAPTURE THERAPY FOR SELECTIVELY OR LOCALLY TARGETING TUMOR TISSUES IN SHORT TIME

ACCUMULATIVE BORON 10 MEDICINE FOR BORON NEUTRON CAPTURE THERAPY FOR SELECTIVELY OR LOCALLY TARGETING TUMOR TISSUES IN SHORT TIME

机译:硼中子累积性治疗的硼10药物,可在短期内选择性或局部靶向肿瘤组织

摘要

The purpose of the present invention is to provide a 10B medicine that can be selectively accumulated in tumor tissues at a low dose in a short time, and can be applied to BNCT. The accumulative 10B medicine comprises a compound containing: a peptide capable of selectively binding to tumor vascular endothelial cells; and 10B, wherein the accumulative 10B medicine is administered to a subject suffering from cancer at a dose of 300-600mg per administration, and is accumulated after the administration such that the concentration of 10B in the cancer tissue of the subject becomes 1ppm or higher.
机译:本发明的目的是提供一种 10 B药物,其可以在短时间内以低剂量选择性地积聚在肿瘤组织中,并且可以应用于BNCT。 10 B累积药物包括一种化合物,该化合物包含:能够选择性结合肿瘤血管内皮细胞的肽;和和 10 B,其中将 10 B累积药物以每次给药300-600mg的剂量施用于患有癌症的受试者,并在给药后累积,受试者的癌组织中 10 B的浓度达到1ppm或更高。

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