MULTI-DRUG MICELLE COMBINATIONS WITH CARBOPLATIN

摘要

Provided are compositions, kits, and methods of treatment including administering to lung, breast, gynecological, and/or gastrointestinal cancer cells a therapeutically effective amount of carboplatin in conjunction with a micelle composition that includes a therapeutically effective amount of paclitaxel, 17-AAG, and rapamycin, wherein the weight ratio of paclitaxel, 17-AAG, rapamycin, and carboplatin is about 1:1:1:1 to about 5:5:1:10 and the micelle includes poly(ethylene glycol)-block-poly(lactic acid) (PEG-b-PLA).