METHOD FOR PREPARING TERTIARY AMINE BASIC COMPONENTS IN RHIZOMA CORYDALIS

摘要

Provided in the present invention is a method for preparing tertiary amine basic components in rhizoma corydalis. The method for preparing basic components provided in the present invention is: reducing berberine quaternary ammonium hydroxide in rhizoma corydalis extracts to protoberberine tertiary amine hydroxide, wherein palmatine and dehydrocorydaline, both of which are two bases with the highest content in rhizoma corydalis, are reduced to tetrahydropalmatine and corydaline respectively. Evaporating the reaction supernatant to dryness after adjusting the pH to neutral, and drying same after desalination to obtain the tertiary amine basic component, wherein the total base content is at least 50%. The preparation method has the advantages of a simple process, high efficiency, high recovery rate and low production cost, and provides good technological schemes for the development of safe, efficient and controllable rhizoma corydalis alkaloid component preparations.