Manufacturing method of egg white protein hydrolysate and use thereof

摘要

The present invention relates to a method for preparing egg white hydrolyzate, and a composition for preventing, improving or treating vascular disease comprising egg white hydrolyzate as an active ingredient. Egg white hydrolyzate according to the present invention strongly activates endothelial nitric oxide synthase (eNOS), which is a major factor for vascular protection, enhances the production of NO (nitric acid), It is released into the blood vessels and induces relaxation of vascular smooth muscle, thereby increasing vascular elasticity, thereby exhibiting vascular relaxation and blood pressure control effects, and inhibiting the secretion or production of allergens such as histidine or TNF-α. It can be usefully used as a composition for the prevention, improvement or treatment of vascular diseases such as hardening, hypertension, coronary artery disease, cerebrovascular disease, peripheral vascular disease or aortic disease.