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ST2 ST2 ANTIGEN BINDING PROTEINS

机译:ST2 ST2抗原结合蛋白

摘要

Compositions and methods related to antigen binding proteins that bind to human ST2, including antibodies, are described in this application. In particular embodiments, the present disclosure provides fully human anti-ST2 antibodies and derivatives and variants thereof. Nucleic acids encoding such antibodies and antibody fragments, variants, and derivatives are also provided. Also provided are methods of making and using such antibodies, including methods of treating and preventing autoimmune and inflammatory disorders.
机译:在本申请中描述了与结合人ST2的抗原结合蛋白(包括抗体)有关的组合物和方法。在特定的实施方案中,本公开提供了完全的人抗ST2抗体及其衍生物和变体。还提供了编码此类抗体以及抗体片段,变体和衍生物的核酸。还提供了制备和使用这种抗体的方法,包括治疗和预防自身免疫和炎性疾病的方法。

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