Block copolymers and self-assembling nanoparticles formed therefrom

摘要

Disclosed is a block copolymer(BCP) capable of self-assembly into nanoparticles for the delivery of hydrophobic cargos. The BCP includes a hydrophobic block that contains a thioether functional group that is susceptible to oxidation, transforming the solubility of the block from hydrophobic to hydrophilic, thereby releasing the hydrophobic cargo of the nanoparticle.