Liposome preparation for delivery of nucleic acids

摘要

Problem to be solved: to provide an efficient delivery of nucleic acids such as siRNA molecules, and a liposome containing liposomes, a composition comprising the same cationic lipid, methods of preparation thereof, and use thereof.Cationic lipidMembrane stabilized lipidsLipid membranes containing PEG amine bound to phospholipidsB) nucleic acid contained in the liposomeC) hyaluronic acid having a molecular weight ranging from 600 to 1000 KDHyaluronic acid binding to the peg amineIncludingA liposome for delivering nucleic acidsHyaluronic acidCoating the external surface of the liposomeLiposomeAnd compositions comprising a plurality of liposomesTheir preparation methodsAnd use method for treating cancer.No selection