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一种抗睾丸hTSC29蛋白的抗体或抗体片段及其应用

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摘要

本发明公开了一种抗睾丸hTSC29蛋白的抗体或抗体片段及其应用，该抗体或抗体片段由保藏号为CCTCC NO：C200952的杂交瘤细胞株hTSC29分泌。通过该抗体或抗体片段能够了解人类精子形成的分子机制和能够对部分男性不育症提供特异性的检测。

著录项

公开/公告号CN101775371B

专利类型发明专利
公开/公告日2012-03-14

原文格式PDF
申请/专利权人唐爱发;颜秋霞;桂耀庭;蔡志明;
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申请/专利号CN200910188640.9
发明设计人唐爱发;颜秋霞;桂耀庭;蔡志明;
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申请日2009-12-02
分类号
代理机构深圳鼎合诚知识产权代理有限公司;
代理人向武桥
地址 518000 广东省深圳市莲花路1120号北京大学深圳医院门诊部8楼
入库时间 2022-08-23 09:08:54

法律信息

法律状态公告日

法律状态信息

法律状态
2015-01-14

未缴年费专利权终止 IPC(主分类):C12N 5/20 授权公告日:20120314 终止日期:20131202 申请日:20091202

专利权的终止
2012-03-14

授权

授权
2010-09-15

实质审查的生效 IPC(主分类):C12N 5/20 申请日:20091202

实质审查的生效
2010-07-14

公开

公开

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1. 一种抗睾丸hTSC29蛋白的抗体或抗体片段及其应用 [P] . 中国专利： CN101775371B . 2012.03.14
2. 一种抗睾丸hT279蛋白的抗体或抗体片段及其应用 [P] . 中国专利： CN101775372B . 2012.01.11
3. pencicillin-binding protein, nucleic acid, antibody or antibody fragment, medicament, pharmaceutical composition, uses of at least one penicillin-binding protein or fragment or variant or fragment thereof, of at least one nucleic acid and of at least one antibody or antibody fragment, in vitro antibody detection methods directed against neisseria meningitidis infection from a penicillin-binding protein, nucleic acid, antibody or an antibody fragment, pharmaceutical composition of at least one penicillin-binding protein or fragment or variant or variant thereof, of at least one nucleic acid and at least one antibody directed against neisseria meningitidis infection from a biological sample of a mammal and in vitro diagnosis of neisseria miningitidis infection from a biological sample from a mammal and monoclonal antibody [P] . BRPI0610802A2 . 2016-11-16

机译：青霉素结合蛋白，核酸，抗体或抗体片段，药物，药物组合物，至少一种青霉素结合蛋白或其片段或变异体或片段，至少一种核酸和至少一种抗体或抗体片段的用途，针对脑膜炎奈瑟菌的青霉素结合蛋白，核酸，抗体或抗体片段感染的体外抗体检测方法，至少一种青霉素结合蛋白或其片段或变异体或变异体，至少一种核酸的药物组合物酸和至少一种针对哺乳动物生物样品中脑膜炎奈瑟氏菌感染的抗体以及来自哺乳动物生物样品中的矿业性奈瑟氏球菌感染的体外诊断和单克隆抗体
4. anti-human sirpa antibody or antigen-binding fragment thereof or antigen-binding antibody mimetic, pharmaceutical composition, combination product, isolated nucleic acid molecule, vector, isolated host cell, polypeptide, methods for making an antibody, in in vitro or ex vivo to determine sirp positive, diagnostic and predictive response cells of a subject, and use of an anti-sirp antibody or antigen-binding fragment thereof or an antibody-binding mimetic in vitro or ex vivo of at least one anti-human sirpa antibody or antigen binding fragment thereof or antigen binding antibody mimetic. [P] . BR112018070823A2 . 2019-02-05

机译：抗人Sirpa抗体或其抗原结合片段或抗原结合抗体模拟物，药物组合物，联合产品，分离的核酸分子，载体，分离的宿主细胞，多肽，在体外或离体制备抗体的方法确定受试者的sirp阳性，诊断和预测反应细胞，以及至少一种抗人sirpa抗体或抗原结合的体外或离体的抗sirp抗体或其抗原结合片段或抗体结合模拟物的用途其片段或抗原结合抗体模拟物。
5. Process for the treatment of glomerulonephritis in a patient in need of this treatment article of manufacture hybridoma antibody 5g.1; 1 isolated nucleic acid protein isolated polypeptide vector recombinant host cell nucleic acid vector process to produce an isolated isolated anti-c5 antibody c5 polypeptide process to produce an isolated anti-c5 antibody protein isolated nucleic acid molecule process to produce an anti-c5 antibody anti-c5 antibody 5g46k fragment 5g27k peptide 5g325aa isolated peptide 5g200aa isolated oligopeptide isolated process to induce an animal to produce an anti- c5 process for identifying an anti-c5 antibody and process for treating a patient in need of complete inhibition [P] . BR9507594A . 1997-09-16

机译：在需要该治疗制品的患者中治疗肾小球肾炎的方法制造杂交瘤抗体5g.1; 1分离的核酸蛋白分离的多肽载体重组宿主细胞核酸载体的过程产生分离的分离的抗c5抗体c5多肽的过程产生分离的抗c5抗体分离的蛋白分子分子过程产生抗c5抗体c5抗体5g46k片段5g27k肽5g325aa分离的肽5g200aa分离的寡肽分离的方法，以诱导动物产生用于鉴定抗c5抗体的抗c5方法以及用于治疗需要完全抑制的患者的方法