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治疗感染的碘聚合物和莫匹罗星复方药物组合物

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摘要

本发明涉及医药领域，具体涉及一种治疗感染的碘聚合物和莫匹罗星复方药物组合物。其特征是：以聚维酮碘和莫匹罗星为活性成分，与药学上可接受的载体制备成复方制剂。通过体外药效研究表明本发明的复方制剂不仅扩大了抗菌谱、而且有效地抑制了莫匹罗星的耐药菌的产生。可以治疗皮肤，黏膜及腔道感染。

著录项

公开/公告号CN102488701B

专利类型发明专利
公开/公告日2013-11-06

原文格式PDF
申请/专利权人江苏德达医药科技有限公司;
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申请/专利号CN201110403187.6
发明设计人梁波;郭靖;陆勇;宋伟;
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申请日2011-12-07
分类号A61K31/79(20060101);A61K31/351(20060101);A61P31/02(20060101);
代理机构32102 南京苏科专利代理有限责任公司;
代理人孙立冰
地址 225300 江苏省泰州市经济开发区药城大道一号2号楼907室
入库时间 2022-08-23 09:16:34

法律信息

法律状态公告日

法律状态信息

法律状态
2016-09-14

专利权的转移 IPC(主分类):A61K 31/79 登记生效日:20160825 变更前: 变更后: 申请日:20111207

专利申请权、专利权的转移
2013-11-06

授权

授权
2012-07-11

实质审查的生效 IPC(主分类):A61K 31/79 申请日:20111207

实质审查的生效
2012-06-13

公开

公开

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1. 治疗感染的碘聚合物和莫匹罗星复方药物组合物 [P] . 中国专利： CN102488701B . 2013.11.06
2. 治疗皮炎的碘聚合物和糖皮质类固醇复方药物组合物 [P] . 中国专利： CN102379893A . 2012-03-21
3. composition, pharmaceutical composition, effervescent dosage form, multiple unit oral oral pharmaceutical composition, extended release pharmaceutical dosage form, enteric coated pharmaceutical dosage form, stable pharmaceutical dosage form for oral administration to mammalian subjects, method for treating diseases acid-related diseases by inhibiting gastric acid secretion, method for treating a bacterial infection caused or caused by helicobacter pylori, process for preparing a compound of formula 3, process for preparing a compound of formula 5, use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion, use of a compound of formula 1 for the preparation of a medicament for treating a bacterial infection caused or caused by helicobacter pyl or use of a compound of formula 1 for the preparation of a medicament for treating gastric acid-related diseases by inhibiting gastric acid secretion [P] . BRPI0617987A2 . 2011-08-16

机译：组合物，药物组合物，泡腾剂型，多单位口服口服药物组合物，缓释药物剂型，肠溶衣药物剂型，向哺乳动物受试者口服给药的稳定药物剂型，通过抑制胃酸治疗疾病的方法酸分泌，治疗由幽门螺杆菌引起或引起的细菌感染的方法，制备式3化合物的方法，制备式5化合物的方法，式1化合物在制备用于治疗胃的药物中的用途通过抑制胃酸分泌来治疗与酸有关的疾病，将式1的化合物用于制备用于治疗由幽门螺杆菌引起或引起的细菌感染的药物，或将式1的化合物用于制备用于治疗的药物通过抑制胃酸分泌来治疗胃酸相关疾病
4. the pharmaceutical method and composition for the prevention or treatment of a disease or an autoimmune or infectious condition, pharmaceutical method and composition for the prevention or treatment of a disease or a condition of blood, pharmaceutical method and composition to modulate the formation of blood cells, Pharmaceutical method and composition to intensify peripheral mobilisation of stem cell, method and pharmaceutical composition for the prevention or treatment of a disease or metabolic condition,Pharmaceutical method and composition for the prevention or treatment of conditions associated with myeloablive chemotherapy doses supported by autologous bone marrow transplantation or peripheral blood stem cells (asct) or allogeneic bone marrow transplantation (bmt),Pharmaceutical method and composition to increase the effect of a stimulating factor in blood cells, method and pharmaceutical composition to intensify the colonization of donor blood stem cells in a myeloablated recept [P] . BRPI0507822A . 2007-07-10

机译：用于预防或治疗疾病或自身免疫或感染性疾病的药物方法和组合物，用于预防或治疗疾病或血液疾病的药物方法和组合物，调节血细胞形成的药物方法和组合物，增强干细胞外周动员的药物方法和组合物，用于预防或治疗疾病或代谢病的方法和药物组合物，用于预防或治疗与自体骨髓移植支持的骨髓活性化疗剂量有关的病症的药物方法和组合物或外周血干细胞（asct）或同种异体骨髓移植（bmt），增加刺激因子在血细胞中的作用的药物方法和组合物，增强骨髓脱钙受体中供体血干细胞定植的方法和药物组合物
5. USE OF A COMPOUND, SUBSTANCE OR COMPOSITION, IN THE PREPARATION OF A SUBSTANCE OR COMPOSITION TO TREAT A VIRAL INFECTION, COMPOUND, SUBSTANCE OR COMPOSITION, THEIR USES FOR, TREATMENT OF A VIRAL INFECTION, AS A TREATMENT OR MEDICATION FROM A VIRAL INFECTION; MEDICINE OR MEDICINE, PROCESS OF PREPARING A COMPOUND AND PROCESS OF TREATING A VIRAL INFECTION IN A HUMAN OR ANIMAL BEING [P] . BR9303733A . 1994-03-15

机译：在制备用于治疗病毒感染，化合物，物质或成分的物质或组合物中使用化合物，物质或组合物，将其用于治疗病毒感染，作为病毒感染的治疗或药物的用途;药物，制备化合物的过程以及治疗人类或动物的病毒感染的过程