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用于鉴定抗原的组合物和方法

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摘要

提供了具有处在规定位置的不连续成员的可复制的库，用于筛选病原生物的抗原。还提供的是使用这种库的方法以及特异性抗原CT788，其在衣原体感染期间诱导T细胞活化。

著录项

公开/公告号CN101437989A

专利类型发明专利
公开/公告日2009-05-20

原文格式PDF
申请/专利权人哈佛大学校长及研究员协会;
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申请/专利号CN200780014310.7
发明设计人 D·E·希金斯;M·N·斯塔恩巴赫;T·吉拉恩;N·R·罗恩;
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申请日2007-02-21
分类号C40B40/02;C40B40/10;C40B30/04;
代理机构中国专利代理(香港)有限公司;
代理人程淼
地址美国马萨诸塞州
入库时间 2023-12-17 21:57:44

法律信息

法律状态公告日

法律状态信息

法律状态
2012-07-11

发明专利申请公布后的视为撤回 IPC(主分类):C40B40/02 公开日:20090520 申请日:20070221

发明专利申请公布后的视为撤回
2009-07-15

实质审查的生效

实质审查的生效
2009-05-20

公开

公开

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3. Modified immunoglobulin, molecule, isolated nucleic acid, cell containing the same, recombinant non-human animal, pharmaceutical composition, vaccine composition, processes for identifying or measuring or detecting a cancer antigen, an antigen from an infectious disease agent, a ligand, and a receptor in a sample. to be tested, kits for detecting a cancer antigen, an infectious disease agent antigen, a cell receptor for an infectious disease agent, a ligand, and a cancer antigen, diagnostic processes or testing for the presence of or a predisposition for the development of a cancer by the increased presence of a cancer antigen, and for the presence of an infectious disease, treatment or prevention of a cancer by the presence of a cancer antigen, of an infectious disease typified by the presence of an antigen infectious disease agent, and a disease caused by an infectious disease agent that binds to a cell receptor, processes for modulating activity of a first member of a binding pair, [P] . BR9815289A . 2001-12-26

机译：修饰的免疫球蛋白，分子，分离的核酸，含有相同免疫球蛋白的细胞，重组非人类动物，药物组合物，疫苗组合物，鉴定或测量或检测癌症抗原的方法，来自传染病原体的抗原，配体和样品中的受体。要测试的试剂盒，用于检测癌症抗原，传染病原体抗原，传染病原体的细胞受体，配体和癌症抗原的试剂盒，诊断过程或测试是否存在或易感通过增加癌症抗原的存在而引起的癌症，以及对于传染病的存在，通过癌症抗原的存在来治疗或预防癌症，以抗原传染病剂的存在为代表的传染病，以及由与细胞受体结合的传染病因子引起的疾病，调节结合对第一个成员的活性的过程，
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机译：分离的负义单链RNA病毒，分离的或重组的核酸或其特定功能的mpv片段，载体，宿主细胞，分离的或重组的蛋白质分子或其特定的功能mpv片段，抗原，抗体，将病毒分离物鉴定为mpv，病毒分离物，用于病毒学和血清学诊断哺乳动物mpv感染的方法，用于诊断mpv感染的诊断试剂盒，病毒，核酸，载体，细胞宿主，蛋白质分子或其片段，抗原的用途，或抗体，药物组合物，用于治疗或预防mpv感染和呼吸道疾病以及获得可用于治疗疾病的抗病毒剂的方法。呼吸道，抗病毒药，病毒药的使用，禽apv感染的病毒学诊断和逻辑诊断方法，诊断测试的使用以及检测样品中针对mpv的抗体的方法
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