Comparison of serum lead level in oral opium addicts with healthy control group

摘要

Lead poisoning can effect on the nervous system, endocrine, renal, reproductive and hematopoiesis. Present study is planned for investigating this issue between patients that use from oral opium and they are at risk of chronic lead poisoning.udMaterials and methods: present study was historical cohort in terms of lead poisoning in which patients admitted to the oral opium. 20 number of these patients selected after getting consent for participate in this study randomly. They assessed and compared with control group for lead poisoning symptoms, examination for possible symptoms of lead poisoning, laboratory studies included blood lead level, U/A in terms of protein, Glucose and Phosphate, CBC, RETIC Uric Acid, BUN, PBS lipid profile and LFT after registration of personal details.udFindings: the average of blood lead level was 8.49± 5.34 Microgram per deciliter in case group and 4.2 ±4.1 Microgram per deciliter in control group that was significant difference on base of Mann_Whitney U test (p- value=0.005). Difference of WBC and MCV between case group and control group was significant. Difference between two groups was not significant For another variables.udResults: present study findings show that blood lead level were higher than control group and difference was significant in terms of statistically despite of none of approved signs were found by lead poisoning laboratory in consumers of oral opium. It seems that these people should be evaluated periodically in terms of lead poisoning possibility.udKeywords: Lead, Chronic poisoning, Opium