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The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells

机译：葡糖神经酰胺合酶抑制剂N-（5-金刚烷-1-基-甲氧基-戊基）-脱氧野oji霉素诱导HepG2细胞中固醇调节元件结合蛋白调节的基因表达和胆固醇合成

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Bijl Nora; Scheij Saskia; Houten Sander; Boot Rolf G.; Groen Albert K.; Aerts Johannes M. F. G.;
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1. The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells. [J] . Bijl N, Scheij S, Houten S, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2008,第3期

机译：葡糖神经酰胺合酶抑制剂N-（5-金刚烷-1-基-甲氧基-戊基）-脱氧野oji霉素在HepG2细胞中诱导固醇调节元件结合蛋白调节的基因表达和胆固醇合成。
2. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals. [J] . Hawkins JL, Robbins MD, Warren LC, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2008,第3期

机译：第1位蛋白酶活性的药理抑制作用抑制了固醇调节元件结合蛋白的加工，并降低了培养细胞和实验动物中脂肪酶基因的表达和脂质合成。
3. Large-Scale Synthesis of the Glucosylceramide Synthase Inhibitor N-[5-(Adamantan-1-yl-methoxy)-pentyl]-1-deoxynojirimycin [J] . Tom Wennekes, Bernhard Lang, Michel Leeman Organic process research & development . 2008,第3期

机译：葡萄糖基神经酰胺合酶抑制剂N- [5-（5-金刚烷-1-基-甲氧基）-戊基] -1-脱氧野oji霉素的大规模合成
4. FoxO1 Inhibits Sterol Regulatory Element-binding Protein-1c (SREBP-1c) Gene Expression via Transcription Factors SREBP-1c and LXR in Goat Mammary Epithelial Cells [C] . Q.Y.He, J.Luo, J.Wu The 6th International Symposium on Dairy Cow Nutrition and Milk Quality（第六届“奶牛营养与牛奶质量”国际研讨会）论文集 . -1

机译：FOXO1通过转录因子Srebp-1C和LXR抑制甾醇调节元素结合蛋白-1C（Sreb-1c）基因表达，山羊乳腺上皮细胞
5. Somatic cell and molecular genetic analysis of various Chinese hamster ovary (CHO) mutant cells defective in sterol-dependent regulation of cholesterol biosynthesis and LDL receptor expression. [D] . Hasan, Mazahir Tahir. 1993

机译：各种中国仓鼠卵巢（CHO）突变细胞的体细胞和分子遗传学分析，它们在胆固醇依赖的胆固醇生物合成和LDL受体表达调控中存在缺陷。
6. Growth Factor-induced Phosphorylation of Sterol Regulatory Element-binding Proteins Inhibits Sumoylation Thereby Stimulating the Expression of Their Target Genes Low Density Lipoprotein Uptake and Lipid Synthesis [O] . Mitsumi Arito, Taro Horiba, Satoshi Hachimura, 2008

机译：生长因子诱导的甾醇调节元件结合蛋白的磷酸化抑制氨化从而刺激其靶基因的表达低密度脂蛋白的摄取和脂质的合成
7. Growth Factor-induced Phosphorylation of Sterol Regulatory Element-binding Proteins Inhibits Sumoylation, Thereby Stimulating the Expression of Their Target Genes, Low Density Lipoprotein Uptake, and Lipid Synthesis*S⃞ [O] . Arito, Mitsumi, Horiba, Taro, Hachimura, Satoshi, 2008

机译：生长因子诱导的甾醇调节元件结合蛋白的磷酸化抑制氨化，从而刺激其靶基因的表达，低密度脂蛋白的摄取和脂质合成* S Synthesis

The glucosylceramide synthase inhibitor N-(5-adamantane-1-yl-methoxy-pentyl)-deoxynojirimycin induces sterol regulatory element-binding protein-regulated gene expression and cholesterol synthesis in HepG2 cells

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