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FLT3 mutations have no prognostic impact in elderly patients with acute myeloid leukemia and normal karyotype.

机译：FLT3突变对老年急性髓性白血病和正常核型患者无影响。

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Ferrara F; Criscuolo C; Riccardi C; Izzo T; Pedata M; Copia C; Vicari L; Tarsitano M; Palmieri S; Pane F.;
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年度 2009
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正文语种 eng
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1. FLT3 mutations have no prognostic impact in elderly patients with acute myeloid leukemia and normal karyotype. [J] . Ferrara F, Criscuolo C, Riccardi C American Journal of Hematology . 2009,第8期

机译：FLT3突变对患有急性髓样白血病和正常核型的老年患者没有预后影响。
2. Myeloablative chemotherapy followed by autologous stem cell infusion may overcome the adverse prognostic impact of FLT3 (foetal liver tyrosine kinase 3) mutations in patients with acute myeloid leukaemia and normal karyotype. [J] . Palmieri S, Ferrara F, Leoni F, Hematological oncology . 2007,第1期

机译：自体干细胞灌注清髓性化学疗法可克服FLT3（胎儿肝酪氨酸激酶3）突变对急性髓样白血病和正常核型患者的不良预后影响。
3. TET2 gene mutation is unfavorable prognostic factor in cytogenetically normal acute myeloid leukemia patients with NPM1+ and FLT3-ITD - mutations [J] . TianX., XuY., YinJ., International journal of hematology . 2014,第1期

机译：TET2基因突变是具有NPM1 +和FLT3-ITD-突变的细胞遗传学正常急性髓细胞白血病患者的不良预后因素
4. Ras gene mutation in acute myeloid leukemia and Myelodysplastic syndromes: a meta-analysis of its occurrence and prognostic relevance [C] . Cheng Jingru, Wang Peng, Zhang Tai, International Conference on Advanced Materials and Computer Science . 2016

机译：RAS基因突变在急性髓性白血病和髓细胞增强综合征中：荟萃分析其发生和预后相关性
5. Pharmacology Profiles of ALK and FLT3 Kinase Inhibitors against Non-Small-Cell Lung Cancer Cells and Acute Myeloid Leukemia Cells with Cancer Driver Mutations [D] . 森政道 2019

机译：ALK和FLT3激酶抑制剂对非小细胞肺癌细胞和急性髓系白血病细胞的癌症驱动突变的药理作用
6. Correspondence: Response: Conflicting data on the prognostic significance of FLT3-TKD mutations in cytogenetically normal acute myeloid leukemia (CN-AML) might be related to many factors including techniques used to detect FLT3-TKD differences in patient populations studied and treatment regimens [O] . Susan P. Whitman, Guido Marcucci, Amy S. Ruppert, -1

机译：对应：响应：关于细胞遗传学上正常的急性髓性白血病（CN-AML）中FLT3-TKD突变对预后意义的数据矛盾可能与许多因素有关包括用于检测FLT3-TKD的技术所研究患者人群的差异以及治疗方法养生
7. Response: Conflicting data on the prognostic significance of FLT3-TKD mutations in cytogenetically normal acute myeloid leukemia (CN-AML) might be related to many factors, including techniques used to detect FLT3-TKD, differences in patient populations studied, and treatment regimens [O] . Whitman, Susan P., Marcucci, Guido, Ruppert, Amy S., 2008

机译：回答：关于细胞遗传学上正常的急性髓性白血病（CN-AML）中FLT3-TKD突变的预后意义的数据冲突可能与许多因素有关，包括用于检测FLT3-TKD的技术，所研究患者人群的差异以及治疗方案

FLT3 mutations have no prognostic impact in elderly patients with acute myeloid leukemia and normal karyotype.

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