Compatibility and toxicity of polymer-coated magnetic nanoparticles on mammalian cell systems

摘要

(cont.) produced normal growth curves in the presence of particles. However, the particles do still exhibit some toxicity towards the cells, as the maximum cell density of cells cultured with particles does not reach that of control cultures. Both particles were found to increase the oxygen transfer in an aqueous solution. A 1.5% solution of particle A enhanced the oxygen transfer 41.8% over the control, water, while 1.4% particle B enhanced 15.9% over the control. While particle A has a better effect on oxygen transfer, this particle is not suitable to be used with mammalian cell cultures as it is highly toxic.