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Y-chromosomal haplogroups in male identification: study of a population sample from Portugal (central area)

机译:男性鉴定中的Y染色体单倍群:来自葡萄牙(中心区)的人口样本研究

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摘要

Background: The non-recombining portion of the Y chromosome represents a valuable tool for the study of human population history. The haploid, non-crossing-over behaviour of Y chromosome gives potentials in many aspects resembling the maternally inherited mtDNA. The advantages for forensic casework are obvious. The haploid state makes mixture patterns much simpler; in female/male stain mixtures, pure male DNA profiles may be obtained. Y-chromosome markers are also of extraordinary value to solve selected paternity cases. Methods: Y-chromosomal biallelic markers have been investigated in a population sample from central Portugal (n=117). By combining the allelic state of 10 biallelic markers (YAP-DYS287, SRY-8299, 92R7, 12f2, SRY-1532, SRY-2627, Tat, SY81, M9, LLY22g), we could define the haplogroup to which each sample belonged. Results: This population defined 10 different haplogroups, haplogroup 1 being the most frequent. Conclusion: This study showed a substantial similarity with other Iberian studies; however, this population presents a larger diversity.
机译:背景:Y染色体的非重组部分代表了研究人类历史的宝贵工具。 Y染色体的单倍体,非交叉行为在许多方面都具有类似于母体遗传的mtDNA的潜力。法医案件的优势显而易见。单倍体状态使混合模式更简单。在雌性/雄性染色混合物中,可以获得纯净的雄性DNA图谱。 Y染色体标记对于解决特定的亲子鉴定案例也具有非凡的价值。方法:在葡萄牙中部(n = 117)的人群样本中研究了Y染色体双等位基因标记。通过组合10个双等位标记(YAP-DYS287,SRY-8299、92R7、12f2,SRY-1532,SRY-2627,Tat,SY81,M9,LLY22g)的等位基因状态,我们可以定义每个样品所属的单倍型。结果:该人群定义了10个不同的单倍群,单倍群1最常见。结论:该研究显示与其他伊比利亚研究具有实质性相似性。但是,这一人群具有更大的多样性。

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