Hybridoma technique and monoclonal antibodies for mariculture applications

摘要

Ever since the beginnings of experimental immunology at the end of the nineteenth century, scientists have exploited the specificity of antibodies to detect, isolate and analyze biological material. The power of antibodies as probes for biological structure udunderwent a quantum increase in 1975, when Kohler and Milstein developed the technique for production of Hybridomas