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Complete genome sequence of thermophilic Bacillus smithii type strain DSM 4216T

机译:嗜热Bacillus smithii 型菌株Dsm 4216T的完整基因组序列

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摘要

is a facultatively anaerobic, thermophilic bacterium able to use a variety of sugars that can be derived from lignocellulosic feedstocks. Being genetically accessible, it is a potential new host for biotechnological production of green chemicals from renewable resources. We determined the complete genomic sequence of the B. smithii type strain DSM 4216T, which consists of a 3,368,778 bp chromosome (GenBank accession number CP012024.1) and a 12,514 bp plasmid (GenBank accession number CP012025.1), together encoding 3880 genes. Genome annotation via RAST was complemented by a protein domain analysis. Some unique features ofcentral metabolism in comparison to related organisms included the lack of a standard acetate production pathway with no apparent pyruvate formate lyase, phosphotransacetylase, and acetate kinase genes, while acetate was the second fermentation product.
机译:是一种兼性厌氧,嗜热细菌,能够使用可衍生自木质纤维素原料的多种糖。由于可遗传获取,它是利用可再生资源进行生物技术生产绿色化学品的潜在新宿主。我们确定了B. smithii型菌株DSM 4216T的完整基因组序列,它由3,368,778 bp染色体(GenBank登录号CP012024.1)和12,514 bp质粒(GenBank登录号CP012025.1)组成,一起编码3880个基因。通过RAST进行的基因组注释通过蛋白质域分析得到补充。与相关生物相比,中央代谢的一些独特特征包括缺乏标准的乙酸生产途径,没有明显的丙酮酸甲酸裂解酶,磷酸转乙酰酶和乙酸激酶基因,而乙酸是第二种发酵产物。

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