EFSA CEF Panel (EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids), 2014. Scientific Opinion on Flavouring Group Evaluation 210, Revision 1 (FGE.210Rev1): Consideration of genotoxic potential for α,β-unsaturated alicyclic ketones and precursors from chemical subgroup 2.4 of FGE.19

摘要

The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 13 flavouring substances in Flavouring Group Evaluation 210 (FGE.210) and one additional substance [FL-no: 07.225] in this revision 1 (FGE.210Rev1). In the first version of FGE.210 the Panel concluded that a genotoxic potential could not be ruled out for any of the 13 substances based on data available at that time. The Flavouring Industry has now submitted additional genotoxicity data. The Panel has evaluated these data and concluded that the concern for genotoxic potential is ruled out for eight of the substances [FL-no: 02.105, 07.007, 07.009, 07.011, 07.036, 07.088, 07.091 and 07.170], while for allyl alpha-ionone [FL-no: 07.061] and for alpha-damascone [FL-no: 07.134] and four structurally related substances [FL-no: 07.130, 07.225, 07.226 and 07.231] the concern still remains with respect to genotoxicity.