首页> 外文OA文献 >Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni

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Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni

机译：阐明桥联1,2,4-三氧杂环戊烷，桥联1,2,4,5-四氧杂环己烷，三环单过氧化物，甲硅烷基过氧化物和羟胺衍生物对抗曼氏血吸虫的体外和体内活性

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Cowan Noemi; Yaremenko Ivan A.; Krylov Igor B.; Terentev Alexander O.; Keiser Jennifer;
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1. Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni [J] . Cowan Noemi, Yaremenko Ivan A., Krylov Igor B., Bioorganic and medicinal chemistry . 2015,第16期

机译：阐明桥联的1,2,4-三氧杂环戊烷，桥联的1,2,4,5-四恶烷，三环一过氧化物，甲硅烷基过氧化物和羟胺衍生物对曼氏血吸虫的体外和体内活性
2. Identification of antischistosomal leads by evaluating bridged 1,2,4,5-tetraoxanes, alphaperoxides, and tricyclic monoperoxides [J] . Ingram K., Yaremenko I.A., Krylov I.B., Journal of Medicinal Chemistry . 2012,第20期

机译：通过评估桥联的1,2,4,5-四恶烷，α-过氧化物和三环一过氧化物来鉴定抗血吸虫铅
3. Comparative antimalarial activities and ADME profiles of ozonides (1,2,4-trioxolanes) OZ277, OZ439, and their 1,2-dioxolane, 1,2,4-trioxane, and 1,2,4,5-tetraoxane isosteres [J] . Wang X., Dong Y., Wittlin S., Journal of Medicinal Chemistry . 2013,第6期

机译：臭氧化物（1,2,4-三氧戊环）OZ277，OZ439及其1,2-二氧戊环，1,2,4-三氧六环和1,2,4,5-四氧六环等甾体的比较抗疟活性和ADME谱
4. Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity [O] . Jennifer M. Fitzpatrick, Jose M. Fuentes, Iain W. Chalmers, -1

机译：曼氏血吸虫精氨酸酶与人类直系同源物具有功能相似性但酶促活性依赖于二硫键
5. Identification of antischistosomal leads by evaluating peroxides of beta-dicarbonyl compounds and their heteroanalogs : bridged 1,2,4,5-tetraoxanes and alphaperoxides, and beta,delta-triketones: tricyclic monoperoxides [O] . Ingram K., Yaremenko I. A., Krylov I., 2012

机译：通过评估β-二羰基化合物及其杂环化合物的过氧化物来鉴定抗血吸虫基因：桥接的1,2,4,5-四氧杂环戊烷和甲基过氧化物，以及β，δ-三酮：三环单过氧化物

Elucidation of the in vitro and in vivo activities of bridged 1,2,4-trioxolanes, bridged 1,2,4,5-tetraoxanes, tricyclic monoperoxides, silyl peroxides, and hydroxylamine derivatives against Schistosoma mansoni

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