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Accuracy of magnetic resonance imaging in detecting lumbo-sacral nerve root compromise: A systematic literature review

机译:磁共振成像检测腰骶神经根损害的准确性:系统性文献综述

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摘要

Background: MRI is considered to be the diagnostic tool of choice in diagnosing nerve root compromise among patients presenting with clinical suspicion of lumbo-sacral radiculopathy. There exists controversy among researchers and clinicians regarding the diagnostic utility and accuracy of MRI in detecting nerve root compromise and radiculopathy. This review evaluated 4 primary diagnostic accuracy studies that specifically assessed the accuracy of MRI in detecting nerve root compromise, as established in the current literature. Methods: Eight electronic data bases were searched for relevant articles from inception until January 2014. All primary diagnostic studies which investigated the accuracy of MRI in diagnosing nerve root compromise among patients with low back and referred leg symptoms were screened for inclusion. Qualifying studies were retrieved and independently assessed for methodological quality using the 'Quality Assessment of Diagnostic tests Accuracy Studies' criteria. Results: Four studies qualified for inclusion in this review. The sensitivity of MRI in detecting lumbar nerve root compromise was very low at 0.25 (95 % CI) while the specificity was relatively high at 0.92 (95 % CI). Conclusions: There is lack of sufficient high quality scientific evidence in support or against the use of MRI in diagnosing nerve root compression and radiculopathy. Therefore, clinicians should always correlate the findings of MRI with the patients' medical history and clinical presentation in clinical decision making.
机译:背景:在临床怀疑腰s神经根病的患者中,MRI被认为是诊断神经根受损的首选诊断工具。在研究人员和临床医生之间,关于MRI在检测神经根受损和神经根病的诊断实用性和准确性方面存在争议。这篇综述评估了4项主要的诊断准确性研究,这些研究专门评估了MRI在检测神经根受损中的准确性,如当前文献中所述。方法:从开始到2014年1月,从8个电子数据库中搜索相关文章。筛选所有纳入MRI诊断腰背及下肢腿部症状患者神经根受损的准确性的主要诊断研究。检索合格的研究,并使用“诊断测试的质量评估准确性研究”标准对方法学质量进行独立评估。结果:四项研究符合纳入本评价的条件。 MRI检测腰神经根受损的敏感性非常低,为0.25(95%CI),而特异性相对较高,为0.92(95%CI)。结论:缺乏足够的高质量科学证据支持或反对使用MRI诊断神经根受压和神经根病。因此,临床医生在进行临床决策时应始终将MRI的发现与患者的病史和临​​床表现相关联。

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