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Infección de injerto aortobifemoral por Candida parapsilosis. Un germen inhabitual

机译:近平滑念珠菌对主动脉移植物的感染。一种不寻常的细菌

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摘要

BACKGROUND: Aorto-enteric fistula is a rare and potentially lethal entity. Its presentation may be as an enteric-paraprosthetic fistula, due to injury in the gut caused by direct contact with the vascular prosthesis. OBJECTIVE: We report a case of enteric-paraprosthetic fistulae with the unusual finding of Candida parapsilosis as the only isolated pathogen. CLINICAL CASE: A 65-year-old male, smoker, with aortobifemoral revascularisation with dacron due to aortoiliac occlusive disease, and re-intervention for thrombosis of left arm at 6 months. Hospitalisation at 22 months was required due to a toxic syndrome, which was diagnosed as enteric-paraprosthetic fistulae after complementary studies. The graft was removed and an extra-anatomic revascularisation was performed. Microbiology specimens taken from the duodenal segment in contact with the prosthesis showed the prosthetic segment and peri-prosthetic fluid were positive to C. parapsilosis. DISCUSSION: The finding of C. parapsilosis in all cultures taken during surgery, along with negative blood cultures and no other known sources of infection, is of interest. It is an unusual pathogen with low virulence and limited as regards other Candida species. Our patient had no clinical data common to cases of infection with C. parapsilosis, and the mechanism of graft infection is unknown. CONCLUSION: Graft infection by C. parapsilosis may be anecdotal. However, its consequences can also be severe. Microbiological tests can be useful to adjust antimicrobial therapy in the post-operative period, but their usefulness for determining the aetiology is doubtful, as it may be just an incidental finding.
机译:背景:主动脉瘘是一种罕见且可能致命的实体。由于与血管假体直接接触造成肠道损伤,其表现可能是肠副假瘘。目的:我们报告了一例肠副假瘘,其中不寻常的假丝酵母是唯一的病原体。临床案例:一名65岁的男性吸烟者,由于主动脉闭塞性疾病而发生了前胎腹血运重建并有涤纶,并在6个月时再次干预了左臂血栓形成。由于毒性综合症,需要在22个月时住院,经补充研究后被诊断为肠副假体瘘。移除移植物并进行解剖外血管重建。取自与假体接触的十二指肠节段的微生物标本显示,假体节段和假体周围液对副弓形虫呈阳性。讨论:在外科手术期间所有培养物中发现副枝隐孢子虫,以及血液培养阴性,没有其他已知的感染源,这是令人感兴趣的。它是一种不常见的病原体,具有低毒力,相对于其他念珠菌属物种而言受到限制。我们的患者没有感染副寄生虫的病例的临床资料,并且移植物感染的机制尚不清楚。结论:副枝隐孢子虫的嫁接感染可能是轶事。但是,其后果也可能很严重。微生物学检查可在术后调整抗生素治疗中有用,但它们在确定病因方面的有用性值得怀疑,因为这可能只是偶然发现。

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