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Effect of Nicotine on Negative Affect Among More Impulsive Smokers

机译:尼古丁对更多冲动性吸烟者负性影响的研究

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摘要

In the present study, the authors tested the hypothesis that nicotine would provide greater relief from negative affect for more impulsive smokers than for less impulsive smokers. Euthymic adult smokers (N = 70) participated in 2 laboratory sessions, during which they underwent a negative mood induction (music x autobiographical memory), then smoked either a nicotinized or de-nicotinized cigarette. Mixed-effects regression yielded a significant Impulsivity x Condition (nicotinized vs. de-nicotinized) x Time interaction. Simple effects analyses showed that heightened impulsivity predicted greater negative affect relief after smoking a nicotinized cigarette but not after smoking a de-nicotinized cigarette. These data suggest that nicotine may be a disproportionately powerful negative reinforcer for highly impulsive smokers, promoting higher levels of nicotine dependence and inhibiting smoking cessation.
机译:在本研究中,作者检验了以下假设:与较少冲动的吸烟者相比,较冲动的吸烟者尼古丁可带来更大的负面影响缓解。正常的成年吸烟者(N = 70)参加了两次实验室会议,在此期间他们经历了负面的情绪诱导(音乐x自传体记忆),然后吸烟或烟熏。混合效应回归产生了显着的冲动x条件(烟碱化与去烟碱化)x时间相互作用。简单的效果分析表明,冲动性增强后,吸烟后吸烟的负面影响缓解效果会更大,但吸烟后则不再吸烟。这些数据表明,对于高度冲动的吸烟者,尼古丁可能是一种不成比例的强大的负面增强剂,促进了更高水平的尼古丁依赖并抑制了戒烟。

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