STUDY DESIGN: Prospective randomized study.udOBJECTIVE: To compare the clinical outcome after Discover arthroplasty versus anterior cervicaluddiscectomy and fusion (ACDF) in patients treated for symptomatic single-level cervical disc disease.udSUMMARY OF BACKGROUND DATA: Anterior cervical discectomy and fusion (ACDF) is stilludconsidered the "gold standard" for surgical treatment of cervical spine degenerative disc disease.udHowever, results of many studies suggest that it may cause degenerative changes at levelsudimmediately above and below the fusion, known as adjacent segment degenerative disease (ADD).udCervical arthroplasty has recently been introduced as an alternative to standard procedure of ACDF. Itudshowed decreased surgical morbidity, decreased complications from postoperative immobilization andudan earlier return to previous level of function.udMETHODS: One hundred consecutive patients with single-level cervical disc disease, producingudradiculopathy and/or myelopathy were randomly divided into groups to undergo ACDF or Discoverudarthroplasty. All patients were evaluated with pre- and postoperative serial radiographic studies andudclinically, using Neck Disability Index (NDI), Visual Analog Scale (VAS) and neurological status atud3, 6, 12 and 24 months.udRESULTS: The results of our study indicate that cervical arthroplasty using Discover ArtificialudCervical Disc provides favorable clinical and radiological outcomes in follow up period of 24 months.udThere has been significant improvement in clinical parameters, VAS and NDI, at 3, 6, 12 and 24udmonths in arthroplasty group comparing to control group.udCONCLUSION: The Discover artificial cervical disc replacement offers favorable outcome comparedudto ACDF for a single-level cervical disc disease at short- and long-term follow-up in selected patients.
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