A fast atom bombardment mass spectrometry study of tris (3, 6-dioxaheptyl) amine-alkali metal halide complexes and hydrogen bonded complexes

摘要

The objective of this thesis was to demonstrate thepotential of fast atom bombardment mass spectrometry (FABMS)as a probe of condensed phase systems and its possible usesfor the study of hydrogen bonding. FABMS was used to studythree different systems. The first study was aimed atinvestigating the selectivity of the ligandtris(3,6-dioxaheptyl) amine (tdoha) for the alkali metalcations. FABMS results correlated well with infrared and nmrdata. Systems where a crown ether competed with tdoha for agiven alkali metal cation were also investigated by fast atombombardment. The results were found to correlate with thecation affinity of tdoha and the ability of the crown ether tobind the cation.In the second and third studies, H-bonded systemswere investigated. The imidazole-electron donor complexeswere investigated and FABMS results showed the expected H-bondstrength of the respective complexes. The effects ofconcentration, liquid matrix, water content, deuteriumexchange, and pre-ionization of the complex were alsoinvestigated. In the third system investigated, the abundanceof the diphenyl sulfone-ammonium salt complexes (presumablyH-bonded) in the FABMS spectrum were found to correlatewith qualitative considerations such as steric hindrance andstrength of ion pairs.