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Multi-electrode nerve cuff recording - model analysis of the effects of finite cuff length

机译:多电极神经袖带记录 - 有限袖带长度影响的模型分析

摘要

The effect of finite cuff length on the signals recorded by electrodes at different positions along the nerve was analysed in a model study. Relations were derived using a one-dimensional model. These were evaluated in a more realistic axially symmetric 3D model. This evaluation indicated that the cuff appeared shorter because of edge effects at the beginning and end of the cuff. The method for velocity selective filtering introduced by Donaldson was subsequently analysed. In this method, velocity selective filtering is achieved by summing the signals of subsequent tripoles after applying time shifts tuned to a certain conduction velocity. It was also found that the optimum electrode distance for a given cuff length for maximum summed RMS of symmetrical tripoles in the cuff is larger than when evaluating peak-peak amplitudes of single fibre action potentials. Velocity selective filtering yields better selectivity when using symmetrical tripoles, but may yield larger signal RMS when using the wider asymmetrical tripoles, potentially allowing for shorter cuffs. It is speculated that application of a multi-electrode reference may improve velocity selectivity for asymmetrical tripoles.
机译:在模型研究中分析了有限袖带长度对电极沿神经不同位置记录的信号的影响。关系是使用一维模型导出的。这些在更逼真的轴向对称3D模型中进行了评估。该评估表明,袖带由于在袖带开始和末端的边缘效应而显得较短。随后分析了唐纳森提出的速度选择滤波方法。在这种方法中,通过在应用调谐到特定传导速度的时移之后对随后的三极管的信号求和来实现速度选择性滤波。还发现,对于给定的袖带长度,对于袖带中对称三极管的最大总RMS而言,最佳电极距离大于评估单纤维动作电位的峰-峰值幅度时的最佳距离。当使用对称的三极管时,速度选择性滤波会产生更好的选择性,但是当使用较宽的非对称三极管时,可能会产生较大的信号RMS,从而可能会缩短袖带。据推测,多电极参考的应用可以提高对不对称三极管的速度选择性。

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