Silicon oxynitride microspheres as stationary phase for high performance liquid chromatography

摘要

Porous spherical silicon oxynitride material exhibits much improvement of chemical stability under high pH mobile phase condition, which can be used as the stationary phase in hydrophilic interaction chromatography mode, and modified to give hydrophobic surface through the interaction of surface Si-NH2 and Si-NH-Si groups with functionalized reagents.