Formation of pseudo3rotaxanes containing calix-bis-crowns and secondary ammonium ions and their thermodynamic stabilities in a solution: preorganization by second macrocycle and nonallosteric behavior exhibited by large crown cavities

摘要

This paper describes the formation of pseudo[3]rotaxanes containing calix[4]-bis-crowns, exhibiting a 1,3-alternate conformation and large crown cavities, and secondary ammonium ions. The first and second association constants of pseudo[3]rotaxane formation are moderate (K1 = 175, K2 = 100 M−1) and are higher than that of the corresponding pseudo[2]rotaxane (K = 24 M−1), consisting of a calix[4]-mono-crown and the same secondary ammonium ion.