USE OF ANTI-DKK1 MONOCLONAL ANTIBODY FOR TREATMENT OF LIVER CANCER

机译：抗DKK1单克隆抗体在治疗肝癌中的应用

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A method of treating liver cancer comprising administering anti-DKKl monoclonal antibody to a subject in need thereof. Anti-DKKl monoclonal antibody can also be administered for preventing or ameliorating cancer metastasis and for neutralizing serum and tissue DKKl in liver cancer patients. The use of anti-DKKl monoclonal antibodies is based on the discovery of the upregulation of DKKl in human liver cancer.

机译：一种治疗肝癌的方法，其包括向有此需要的受试者施用抗DKK1单克隆抗体。还可以施用抗DKK1单克隆抗体以预防或改善肝癌患者的癌症转移以及中和血清和组织DKK1。抗DKK1单克隆抗体的使用是基于在人类肝癌中DKK1的上调的发现。

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机译： BRAF 非V600E突变对治疗的转移性结直肠癌患者抗EGFR单克隆抗体的治疗作用的临床意义：基于综合癌症基因组学（BREAC）的抗EGFR单克隆抗体的生物标志物研究研究
2. The COMET Open-label Phase II Study of Neoadjuvant FOLFOX or XELOX Treatment Combined with Molecular Targeting Monoclonal Antibodies in Patients with Resectable Liver Metastasis of Colorectal Cancer [J] . Masato Kataoka, Mitsuro Kanda, Kiyoshi Ishigure, Annals of surgical oncology . 2017,第2期

机译：彗星开放标签期II研究Neoadjuvant Folfox或Xelox治疗结合分子靶向单克隆抗体在结直肠癌的可重症肝转移患者中
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5. Cloning and expression of a biosimilar chimeric monoclonal antibody directed against the human epidermal growth factor receptor and its production in CHO cells for treatment of colo-rectal cancer. [D] . Motiwala, Hatim Maqbulhusen. 2012

机译：针对人表皮生长因子受体的生物仿制药嵌合单克隆抗体的克隆和表达及其在CHO细胞中的产生，用于治疗结肠直肠癌。
6. Comment on ‘Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehensive Cancer genomics (BREAC) study’ [O] . Matthew Dankner, April A. N. Rose 2018

机译：评论 BRAF non-V600E突变对转移性结直肠癌预治疗的抗EGFR单克隆抗体治疗的临床意义：通过综合癌症基因组学（BREAC）研究抗EGFR单克隆抗体的生物标志物研究
7. Comment on ‘Clinical significance of BRAF non-V600E mutations on the therapeutic effects of anti-EGFR monoclonal antibody treatment in patients with pretreated metastatic colorectal cancer: the Biomarker Research for anti-EGFR monoclonal Antibodies by Comprehensive Cancer genomics (BREAC) study’ [O] . Matthew Dankner, April A. N. Rose 2018

机译：评论对预处理转移性结直肠癌患者抗EGFR单克隆抗体治疗抗EGFR单克隆抗体治疗的临床意义：综合癌症基因组学（BREAC）研究对抗EGFR单克隆抗体的生物标志物研究'

USE OF ANTI-DKK1 MONOCLONAL ANTIBODY FOR TREATMENT OF LIVER CANCER

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