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Medicine for treating colon cancer and preparation method thereof

机译:治疗结肠癌的药物及其制备方法

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摘要

The invention discloses a medicine for treating colon cancer and a preparation method thereof, comprising effective medicine ingredients: 3beta-hydroxy-28-nor-ursol-17, 19, 21-triene and medicament prepared from pharmaceutic adjuvants. The medicine comprises the following components by weight percent: 1% to 90% of effective ingredients and 10% to 99% of the pharmaceutic adjuvants.. The structural formula of the effective ingredient of the medicine is C29H44O. The preparation method of the medicine for treating colon cancer comprises the following steps: (1) adding charred radix sanguisorbae taken as a raw medicine material into carbinol or ethanol for repeated extraction, and obtaining fluid extract by filtration; (2) dispersing the fluid extract of the first step with water, and carrying out chloroform extraction, and recycling solvent of the extract liquid to obtain extract; (3) crystallizing solid which is obtained by carrying out the suction filtration on extract of the second step to obtain the effective ingredients of compound medicine; (4) taking the effective ingredients of the medicine according to the weight ratio, and wherein the rest pharmaceutic adjuvants are prepared into the medicament.; The medicine disclosed by the invention is mainly used for treating colon cancer without metastasis symptom and allaying pain of patients in the chemotherapy period after the operation, and has non-toxic side effects.
机译:本发明公开了一种治疗结肠癌的药物及其制备方法,包括有效的药物成分:3β-羟基-28-去甲酚-17、19、21-三烯和由药物佐剂制备的药物。该药物包含以下重量百分比的成分:1%至90%的有效成分和10%至99%的药物佐剂。药物的有效成分的结构式为C29H44O。该治疗结肠癌的药物的制备方法包括以下步骤:(1)在甲醇或乙醇中添加以生药材为焦的焦山参进行重复提取,并通过过滤得到液体提取物。 (2)将第一步的流体提取物分散在水中,进行氯仿提取,回收提取液的溶剂,得到提取物; (3)对第二步的提取物进行抽滤得到的结晶固体,从而得到复方药的有效成分。 (4)按照重量比服用药物的有效成分,并将其余的药物佐剂制成药物。本发明公开的药物主要用于手术后化疗期无转移症状,无患者缓解疼痛的结肠癌的治疗,具有无毒副作用。

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