首页> 外文OA文献 >Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

【2h】

Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

机译：用伊马替尼治疗的CmL患者中BCR-aBL突变的检测实际上总是伴有临床耐药性，aTp磷酸盐结合环（p环）的突变与预后不良有关

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Abstract not available

机译：摘要不可用

著录项

作者
Branford S.; Rudzki Z.; Walsh S.; Parkinson I.; Grigg A.; Szer J.; Taylor K.; Hermann R.; Seymour J.; Arthur C.; Joske D.; Lynch K.; Hughes T.;
展开▼
作者单位

展开▼
年度 2003
总页数
原文格式 PDF
正文语种 eng
中图分类

相似文献

外文文献
中文文献
专利

1. Analysis of Bcr-Abl kinase domain mutations in Korean chronic myeloid leukaemia patients: poor clinical outcome of P-loop and T315I mutation is disease phase dependent. [J] . Kim SH, Kim D, Kim D Hematological oncology . 2009,第4期

机译：在韩国慢性粒细胞白血病患者中，Bcr-Abl激酶结构域突变的分析：P环和T315I突变的不良临床预后与疾病阶段有关。
2. Molecular basis explanation for imatinib resistance of BCR-ABL due to T315I and P-loop mutations from molecular dynamics simulations. [J] . Lee TS, Potts SJ, Kantarjian H, Cancer: A Journal of the American Cancer Society . 2008,第8期

机译：分子动力学模拟对由于T315I和P环突变导致的BCR-ABL伊马替尼耐药的分子基础解释。
3. BCR-ABL Kinase Domain Mutations Exist in Few Imatinib Treated Chronic Myeloid Leukemia (CML) Patients Exhibiting Stable Cytogenetic and Hematologic Responses [J] . Akram Afia Muhammad, Akhtar Tanveer, Chaudhary Asma, Blood: The Journal of the American Society of Hematology . 2018,第NovaelaTreatmentAppr期

机译：在少量伊马替尼处理的慢性骨髓白血病（CML）患者中存在BCR-ABL激酶结构域突变患者表现出稳定的细胞遗传学和血液学反应
4. Detection and epidemiological patterns of drug resistance mutations in NYS Plasmodium falciparum clinical malaria specimens [D] . Conaway, Jennifer L. 2012

机译：NYS疟原虫临床疟疾标本中毒性抗药性突变的检测和流行病学模式
5. Presence of novel compound BCR-ABL mutations in late chronic and advanced phase imatinib sensitive CML patients indicates their possible role in CML progression [O] . Afia Muhammad Akram, Zafar Iqbal, Tanveer Akhtar, 2017

机译：慢性和晚期伊马替尼敏感的CML患者中存在新的复合BCR-ABL突变表明其可能在CML进展中发挥作用
6. Detection of BCR-ABL kinase domain mutations in CD34+ cells from newly diagnosed chronic phase CML patients and their association with imatinib resistance [O] . Zafar Iqbal, Ijaz Shah, Aamer Aleem, 2011

机译：新诊断的慢性CML患者CD34 +细胞中BCR-ABL激酶结构域突变的检测及其与伊马替尼耐药性的关系

Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅