首页> 外文OA文献 >Indigenous children living nearby plantations with chlorpyrifos-treated bags have elevated 3,5,6-trichloro-2-pyridinol (TCPy) urinary concentrations.
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Indigenous children living nearby plantations with chlorpyrifos-treated bags have elevated 3,5,6-trichloro-2-pyridinol (TCPy) urinary concentrations.

机译:生活在毒死蜱处理袋附近种植园的土着儿童尿液浓度升高了3,5,6-三氯-2-吡啶醇(TCpy)。

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摘要

Background: The USEnvironmentalProtectionAgencyvoluntaryphased-outresidentialuseofchlor-pyrifosin2001.Incontrast,inCostaRica,chlorpyrifos-treatedbagsareincreasinglyusedtoprotectbananaandplantainfruitsfrominsectsandtofulfillproductstandards,eveninpopulatedareas.Objectives: To evaluatechildren’sexposuretochlorpyrifosinvillagessituatednearbybananaplanta-tions andplantainfarmsinCostaRica.Methods: The studytargetedtwovillageswithuseofchlorpyrifos-treatedbagsinnearbybananaplantationsandplantainfarmsandonevillagewithmainlyorganicproduction.For140childrenfromthese villages,mostlyindigenousNg¨abe andBribri,parent-interviewsandurinesamples(n¼207) wereobtained.Urinary3,5,6-trichloro-2-pyridinol(TCPy)levelsweremeasuredasabiomarkerforchlor-pyrifosexposure.Inthebananaandplantainvillagealsoenvironmentalcontaminationtochlorpyrifoswas explored.Results: Children fromthebananaandplantainvillageshadstatisticallysignificanthigherurinaryTCPyconcentrationsthanchildrenfromthereferentvillage;2.6and2.2versus1.3 mg/g creatinine,respectively.Chlorpyrifoswasdetectedin30%oftheenvironmentalsamplesaswellasin92%ofthehand/footwashsamples.FormorethanhalfofthechildrentheirestimatedintakeexceededtheUSEPAchronic populationadjusteddose.Forsome,theacutepopulationadjusteddoseandthechronicreferencedosewerealsoexceeded.Conclusions: Our resultssuggestthatchildrenlivingnearbyplantationswithchlorpyrifos-treatedbagsare exposedtochlorpyrifoslevelsthatmayaffecttheirhealth.Interventionstoreducechlorpyrifosexposurearelikelytoimprovechildren’shealthandenvironmentinbananaandplantaingrowingregions.
机译:背景:USEnvironmentalProtectionAgencyvoluntaryphased-outresidentialuseofchlor-pyrifosin2001.Incontrast,inCostaRica,毒死蜱treatedbagsareincreasinglyusedtoprotectbananaandplantainfruitsfrominsectsandtofulfillproductstandards,eveninpopulatedareas.Objectives:要evaluatechildren'sexposuretochlorpyrifosinvillagessituatednearbybananaplanta-蒸发散andplantainfarmsinCostaRica.Methods:本studytargetedtwovillageswithuseofchlorpyrifos-treatedbagsinnearbybananaplantationsandplantainfarmsandonevillagewithmainlyorganicproduction.For140childrenfromthese村庄,mostlyindigenousNg¨abeandBribri,家长interviewsandurinesamples(n¼207)在香蕉和大蕉村中也检测了尿中的3,5,6-三氯-2-吡啶醇(TCPy)含量作为生物标志物。还研究了香蕉和大蕉村对环境的毒死率。结果:从香蕉和大蕉中分离出的儿童从2.6到3.0的比例明显高于该值。毫克/克肌酸酐,respectively.Chlorpyrifoswasdetectedin30%oftheenvironmentalsamplesaswellasin92%ofthehand / footwashsamples.FormorethanhalfofthechildrentheirestimatedintakeexceededtheUSEPAchronic populationadjusteddose.Forsome,theacutepopulationadjusteddoseandthechronicreferencedosewerealsoexceeded.Conclusions:我们resultssuggestthatchildrenlivingnearbyplantationswithchlorpyrifos-treatedbagsare exposedtochlorpyrifoslevelsthatmayaffecttheirhealth.Interventionstoreducechlorpyrifosexposurearelikelytoimprovechildren'shealthandenvironmentinbananaandplantaingrowingregions。

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