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Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6): Chemical Synthesis of Catalytically Active Calstabin and Mutants

机译：完全活性的亲和素钙稳定蛋白2（FKBP12.6）的总化学合成，重折叠和晶体结构：催化活性钙稳定蛋白和突变体的化学合成

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International audience

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Bacchi, Marine; Jullian, Magali; Sirigu, Serena; Fould, Benjamin; Huet, Tiphaine; Bruyand, Lisa; Antoine, Mathias; Vuillard, Laurent; ronga, luisa; Chavas, Leonard M. G.; Nosjean, Olivier; Ferry, Gilles; Puget, Karine; Boutin, Jean A.;
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1. Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6) [J] . Bacchi Marine, Jullian Magali, Sirigu Serena, Protein Science: A Publication of the Protein Society . 2016,第12期

机译：完全活性的亲免疫性钙结合蛋白2（FKBP12.6）的总化学合成，重折叠和晶体结构
2. Stereochemical course of enzymatic enolpyruvyl transfer and catalytic conformation of the active site revealed by the crystal structure of the fluorinated analogue of the reaction tetrahedral intermediate bound to the active site of the C115A mutant [J] . Skarzynski T., Lees WJ., Walsh CT., Biochemistry . 1998,第8期

机译：反应四面体中间体的氟化类似物的晶体结构结合到C115A突变体的活性位点上，揭示了酶促烯醇式丙酮酸转移的立体化学过程和活性位点的催化构象
3. Using Nanosized, Homogeneous, and Heterogeneous Catalytic Systems in Organic Synthesis: Changing the Structure of Active Center in Chemical Reactions in Solution [J] . V. P. Ananikov, I. P. Beletskaya Nanotechnologies in Russia . 2010,第1a2期

机译：在有机合成中使用纳米级，均相和均相催化体系：改变溶液中化学反应中活性中心的结构
4. Synthesis and Characterization of Self-Organized Microstructures with Chemically Active Surfaces and Evaluation of their Technical Utility [C] . Alok Singh, Michael A.Markowitz, Paul E.Schoen, International symposium on chemically modified surfaces . 1999

机译：具有化学活性表面的自组织微观结构的合成与表征及其技术效用评价
5. Part One. Synthesis of optically active tryptophan derivatives with potential activity as indoleamine 2,3-dioxygenase inhibitors: An approach via asymmetric catalytic hydrogenation. Part Two. Design, synthesis and pharmacology of selective ligands for alpha1-containing GABA(A)/benzodiazepine receptor subtypes: SAR studies of beta-carbolines at positions -3 and -6 and their corresponding bivalent ligands. Part Three. First enantiospecific total synthesis of the important biogenetic intermediates, (+)-polyneuridine and (+)-polyneuridine aldehyde, as well as 16-epi-vellosimine and macusine A. [D] . Yin, Wenyuan. 2007

机译：第一部分。具有吲哚胺2,3-二加氧酶抑制剂潜在活性的旋光色氨酸衍生物的合成：一种通过不对称催化氢化的方法。第二部分。含α1的GABA（A）/苯并二氮杂receptor受体亚型的选择性配体的设计，合成和药理作用：位于-3和-6位的β-咔啉及其相应的二价配体的SAR研究。第三部分。重要生物遗传中间体，（+）-聚神经氨酸和（+）-聚神经氨酸醛，以及16-表-维西辛和Macusine A的首次对映体全合成。
6. Total chemical synthesis refolding and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6) [O] . Marine Bacchi, Magali Jullian, Serena Sirigu, 2016

机译：完全活性的亲免疫性钙蛋白2（FKBP12.6）的总化学合成重折叠和晶体结构
7. Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6): Chemical Synthesis of Catalytically Active Calstabin and Mutants [O] . Bacchi, Marine, Jullian, Magali, Sirigu, Serena, 2016

机译：完全活性的亲和素钙稳定蛋白2（FKBP12.6）的总化学合成，重折叠和晶体结构：催化活性钙稳定蛋白和突变体的化学合成

Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 (FKBP12.6): Chemical Synthesis of Catalytically Active Calstabin and Mutants

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