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A complete graphical criterion for the adjustment formula in mediation analysis

机译:调解分析中调整公式的完整图形标准

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摘要

Various assumptions have been used in the literature to identify natural direct and indirect effects in mediation analysis. These effects are of interest because they allow for effect decomposition of a total effect into a direct and indirect effect even in the presence of interactions or non-linear models. In this paper, we consider the relation and interpretation of various identification assumptions in terms of causal diagrams interpreted as a set of non-parametric structural equations. We show that for such causal diagrams, two sets of assumptions for identification that have been described in the literature are in fact equivalent in the sense that if either set of assumptions holds for all models inducing a particular causal diagram, then the other set of assumptions will also hold for all models inducing that diagram. We moreover build on prior work concerning a complete graphical identification criterion for covariate adjustment for total effects to provide a complete graphical criterion for using covariate adjustment to identify natural direct and indirect effects. Finally, we show that this criterion is equivalent to the two sets of independence assumptions used previously for mediation analysis.
机译:文献中使用了各种假设来确定调解分析中的自然直接和间接影响。这些效果是令人感兴趣的,因为即使在存在交互作用或非线性模型的情况下,它们也可以将总效果分解为直接和间接效果。在本文中,我们根据因果图来解释各种识别假设的关系和解释,这些因果图被解释为一组非参数结构方程。我们表明,对于这样的因果图,文献中描述的两组用于识别的假设实际上是等效的,这是指,如果任何一组假设都适用于所有模型,可以推导特定的因果图,则另一组假设还将适用于所有推导该图的模型。此外,我们在先前的工作的基础上,完成了对总效应的协变量调整的完整图形识别标准,从而为使用协变量调整来识别自然的直接和间接效应提供了完整的图形标准。最后,我们表明该标准等同于先前用于调解分析的两组独立性假设。

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