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Antifouling coatings for dental implants: Polyethylene glycol-like coatings on titanium by plasma polymerization

机译:用于牙科植入物的防污涂层:通过等离子体聚合在钛上的聚乙二醇类涂层

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摘要

Titanium dental implants are commonly used for the replacement of lost teeth, but they present a considerable number of failures due to the infection on surrounding tissues. The aim of this paper is the development of a polyethylene glycol-like (PEG-like) coating on the titanium surface by plasma polymerization to obtain a novel improved surface with suitable low bacterial adhesion and adequate cell response. Surface analysis data of these coatings are presented, in particular, water contact angle, surface roughness, and film chemistry, demonstrating the presence of a PEG-like coating. Streptococcus sanguinis and Lactobacillus salivarius bacterial adhesion assays showed a decreased adhesion on the plasma polymerized samples, while cell adhesion of fibroblasts and osteoblasts on the treated surfaces was similar to control surfaces. Thus, the PEG-like antifouling coating obtained by plasma polymerization on Ti confers this biomaterial's highly suitable properties for dental applications, as they reduce the possibility of infection while allowing the tissue integration around the implant. (C) 2015 American Vacuum Society.
机译:钛牙植入物通常用于替换掉的牙齿,但是由于周围组织的感染,它们会导致相当多的失败。本文的目的是通过等离子体聚合在钛表面上开发一种聚乙二醇样(PEG样)涂层,以获得具有合适的低细菌粘附力和足够的细胞反应性的新型改良表面。给出了这些涂层的表面分析数据,特别是水接触角,表面粗糙度和薄膜化学性质,证明了PEG类涂层的存在。血链球菌和唾液乳杆菌细菌粘附试验表明,血浆聚合样品上的粘附减少,而处理后的表面上的成纤维细胞和成骨细胞的细胞粘附与对照表面相似。因此,通过在Ti上进行等离子聚合而获得的PEG类防污涂层赋予了这种生物材料非常适合牙科应用的特性,因为它们减少了感染的可能性,同时允许植入物周围的组织整合。 (C)2015美国真空学会。

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