首页> 外文OA文献 >Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor

【2h】

Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor

机译：在易断裂键处用哌啶酸取代脯氨酸将HIV蛋白酶的肽底物转化为选择性抑制剂

页面导航

著录项
引文网络
相似文献
相关主题

著录项

作者
Copeland Terry D.; Wondrak Ewald M.; Roberts Michael M.; Oroszlan Stephen; Tőzsér József;
展开▼
作者单位

展开▼
年度 2017
总页数
原文格式 PDF
正文语种 eng
中图分类

相似文献

外文文献
中文文献
专利

1. In Vitro Processing of HIV-1 Nucleocapsid Protein by the Viral Proteinase:Effects of Amino Acid Substitutions at the Scissile Bond in the Proximal Zinc Finger Sequence [J] . Jozsef Tozser, Sergey Shulenin, John M.Louis, Biochemistry . 2004,第14期

机译：病毒蛋白酶在体外加工HIV-1核衣壳蛋白：近端锌指序列中易断裂键处氨基酸取代的影响
2. Stereochemical Sequence Ion Selectivity: Proline versus Pipecolic-acid-containing Protonated Peptides [J] . Abutokaikah Maha T., Guan Shanshan, Bythell Benjamin J. Journal of the American Society for Mass Spectrometry . 2017,第1期

机译：立体化学序列离子选择性：脯氨酸与含苯乙烯酸的质子化肽
3. HEXAFLUOROACETONE AS ACTIVATING AND PROTECTING REAGENT IN AMINO ACID AND PEPTIDE CHEMISTRY .19. AN EFFICIENT APPROACH TO THE FAMILY OF 4-SUBSTITUTED PIPECOLIC ACIDS - SYNTHESES OF 4-OXO-, CIS-4-HYDROXY-, AND TRANS-4-HYDROXY-L-PIPECOLIC ACIDS FROM L-A [J] . Golubev A., Burger K., Sewald N. Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 1995,第12期

机译：六氟丙酮作为氨基酸和肽化学中的活化和保护试剂.19。一种由4位取代的直链氨基酸组成的有效方法-由L-A合成4-OXO-，CIS-4-羟基-和反式-4-羟基-L-PI酸
4. A Systematic Investigation of Proline vs. Pipecolic Acid-containing Peptide Fragmentation Chemistry [C] . Maha T. Abutokaikah, Shanshan Guan, Benjamin J. Bythell ASMS Conference on Mass Spectrometry and Allied Topics . 2016

机译：脯氨酸与含吡啶酸肽碎片化学的系统研究
5. (1) Conformational heterogeneity about proline and pipecolic acid peptide bonds. (2) Structure of substrate analogs bound to enoyl-CoA hydratase [D] . Wu, Wen-Jin. 1999

机译：（1）脯氨酸和胡椒酸肽键的构象异质性。（2）与烯酰辅酶A水合酶结合的底物类似物的结构
6. Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis. [O] . Lisbeth S Laursen, Michael T Overgaard, Claus G Nielsen, 2002

机译：通过诱变和合成肽分析评估金属蛋白酶妊娠相关血浆蛋白A（PAPP-A）的底物特异性：远离易裂键的底物残基对于蛋白水解至关重要。
7. SUBSTITUTION OF PROLINE WITH PIPECOLIC ACID AT THE SCISSILE BOND CONVERTS A PEPTIDE SUBSTRATE OF HIV PROTEINASE INTO A SELECTIVE INHIBITOR [O] . Terry D. Copel, Ewald M. Wondrak, Jozsef Tozser, 1990

机译：在裂解键上用哌啶酸取代脯氨酸将HIV蛋白酶的多肽基质转化为选择性抑制剂
8. Direct Selective Acylation of an Unactivated C-H Bond in a Caged Hydrocarbon.Approach to Systems for C-H Bond Functionalization That Proceed Catalytically and Selectively at High Substrate Conversion [R] . Prosser-McCartha, C. M., Hill, C. L. 1990

机译：笼型烃中未活化C-H键的直接选择性酰化。用于C-H键官能化的系统，在高基质转化下催化和选择性地进行

Substitution of proline with pipecolic acid at the scissile bond converts a peptide substrate of HIV proteinase into a selective inhibitor

著录项

引文网络

相似文献

相关主题

期刊订阅