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Effect of PLLA/Keratin Ratio on Mechanical and Physical Properties of Electrospun Nonwoven Fibrous Membrane

机译:pLLa /角蛋白比例对静电纺丝非织造纤维膜力学和物理性能的影响

摘要

Mechanical and physical properties are potentially very important for biomaterials to be used as scaffolds. To investigate the effect of adding keratin to polylactic acid (PLLA) on the mechanical and physical properties of electrospun nonwoven fibrous membranes, a series of experiments were conducted, with PLLA/keratin mass proportions of 1:0, 2:1, 1:1, 1:2, 1:4 and 1:8 respectively. Measured mechanical and physical properties include tensile property, compressional property, water vapor permeability, moisture content and moisture management property. The results show that with an increase in the keratin content, tensile property of above membranes decreased; while moisture content and hydrophilicity are increased; compressional property and water vapor permeability, however, are not influenced significantly. It could be concluded from the experimental results that adding keratin into PLLA would significantly change some important mechanical and physical properties of electrospun nonwoven fibrous membranes, which could influence their performances as scaffolds for tissue engineering.
机译:对于用作支架的生物材料而言,机械和物理性能可能非常重要。为了研究将角蛋白添加到聚乳酸(PLLA)中对电纺非织造纤维膜的机械和物理性能的影响,进行了一系列实验,其中PLLA /角蛋白的质量比例为1:0、2:1、1:1 ,1:2、1:4和1:8。测得的机械和物理性质包括拉伸性质,压缩性质,水蒸气渗透性,水分含量和水分管理性质。结果表明,随着角蛋白含量的增加,上述膜的拉伸性能下降。同时增加水分含量和亲水性;然而,压缩性能和水蒸气渗透性并未受到显着影响。从实验结果可以得出结论,将角蛋白添加到PLLA中将显着改变电纺非织造纤维膜的一些重要的机械和物理性能,这可能会影响其作为组织工程支架的性能。

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