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Efficient Synthesis of Optically Active b-Substituted Pyroglutamic Acid and Its Application toward the Synthesis of Biologically Active Molecules

机译：光学活性b-取代焦谷氨酸的高效合成及其在生物活性分子合成中的应用

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博士(理学)

机译：博士(理学)

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山田健;
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年度 2007
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正文语种 jpn
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1. From N-triisopropylsilylpyrrole to an optically active C-4 substituted pyroglutamic acid: total synthesis of penmacric acid [J] . Christophe Berini, Nadia Pelloux-Leon, Frederic Minassian, Organic & biomolecular chemistry . 2009,第21期

机译：从N-三异丙基甲硅烷基吡咯到光学活性的C-4取代焦谷氨酸：泛酸的全合成
2. SYNTHESIS OF OPTICALLY ACTIVE (R)- AND (S)-beta-ARGININE FROM PYROGLUTAMIC ACID [J] . Yasuno Yoko, Sawai Akira, Sekihara Ai, Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2020,第1期

机译：从焦蛋白酸合成光学活性（R） - 和 - β-精氨酸
3. Efficient and general method for the synthesis of benzopyrans by ethylenediamine diacetate-catalyzed reactions of resorcinols with alpha,beta-unsaturated aldehydes.One step synthesis of biologically active(+-)-confluentin and(+-)-daurichromenic acid [J] . Yong Rok Lee, Jung Hyun Choi, Sang Heum Yoon Tetrahedron letters: The International Journal for the Rapid Publication of Preliminary Communications in Organic Chemistry . 2005,第44期

机译：乙二胺二乙酸酯催化间苯二酚与α，β-不饱和醛反应合成苯并吡喃的有效和通用方法。一步法合成生物活性（+-）-confluentin和（+-）-柔红铬酸
4. SYNTHESIS AND UTILIZATION OF HYPERBRANCHED POIN(AMINO ACIDS) AS CARRIERS OF BIOLOGICALLY ACTIVE SUBSTANCES: PROBLEMS AND SOLUTIONS [C] . G. VLASOV NATO Advanced Research Workshop on Environmental and Biological Risks of Hybrid Organic-Silicon Nanodevices . 2009

机译：超支化Poin（氨基酸）作为生物活性物质的载体的合成与利用：问题和解决方案
5. Part I. Hz166, a novel γ-aminobutyric acid (A) receptor subtype-selective ligand active against neuropathic pain Part II. The first enantiospecific, stereospecific total synthesis of the C-19 methyl substituted sarpagine indole alkaloids 19(S), 20(R), 19-(S),20(R)dihydroperaksine-17-al and peraksine Part III. Application of metal-carbenoid chemistry and Brönsted acid mediated cyclization of enaminones for the rapid and efficient access to the tetracyclic (ABCE) skeleton of the Strychnos alkaloids contained in bisindole alkaloids [D] . Edwankar, Rahul V. 2010

机译：第I部分：Hz166，一种新型的对神经性疼痛有活性的γ-氨基丁酸（A）受体亚型选择性配体。 C-19甲基取代的沙雷帕金吲哚生物碱19（S），20（R），19-（S），20（R）dihydroperaksine-17-al和peraksine第三部分的第一个对映体特异性，立体定向全合成。金属类固醇化学和布朗斯台德酸介导的烯胺酮环化的应用，用于快速有效地获取双吲哚生物碱中马兜铃生物碱的四环（ABCE）骨架
6. Application of aziridinium ring opening for preparation of optically active diamine and triamine analogues: Highly efficient synthesis and evaluation of DTPA-based MRI contrast enhancement agents [O] . Xiang Sun, Yunwei Chen, Ningjie Wu, -1

机译：氮丙啶鎓开环在制备旋光二胺和三胺类似物中的应用：基于DTPA的MRI造影剂的高效合成和评估
7. Studies on Optically Active Amino Acids. XVI. Studies on α-Alkyl-α-amino Acids. XI. Synthesis of R-α-Methylphenylalanine from S (+)-2-Methyl-3-phenylpropionic Acid by the Direct Conversion of the optically Active C-H Bond into the C-N Bond [O] . SHIRO TERASHIMA, SHUNICHI YAMADA 1968

机译：对光学活性氨基酸的研究。 XVI。研究α-烷基-α-氨基酸。 XI。通过将光学活性C-H键的直接转化为C-N键的基于S（+） - 2-甲基-3-苯基丙酸的R-α-甲基苯基丙氨酸的合成
8. Stereoselective synthesis of optically active aspartic acid from derivatives of fumaric acid and maleic acid [R] . Harada, K., Matsumoto, K. 1966

机译：从富马酸和马来酸的衍生物立体选择性合成光学活性的天冬氨酸

Efficient Synthesis of Optically Active b-Substituted Pyroglutamic Acid and Its Application toward the Synthesis of Biologically Active Molecules

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