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Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor

机译：未成熟橙（aurantii fructus immaturus）和Citrus Unshiu peel（Citri unshiu pericarpium）的提取物通过上调pregnane X Receptor诱导p-糖蛋白和细胞色素p450 3a4表达

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Naoto Okada; Aki Murakami; Shiori Urushizaki; Misa Matsuda; Kazuyoshi Kawazoe; Keisuke Ishizawa;
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1. Effect of oral administration of water-soluble extract from citrus peel (Citrus unshiu) on suppressing alcohol-induced fatty liver in rats [J] . Ho-Young Park, Yongkon Park, Youngsuk Lee, Food Chemistry . 2012,第3期

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2. Neuroprotective effect of Citrus unshiu immature peel and nobiletin inhibiting hydrogen peroxide-induced oxidative stress in HT22 murine hippocampal neuronal cells [J] . Hyun Woo Cho, Su Young Jung, Gyeong Hwan Lee, Pharmacognosy magazine . 2015,第Suppla2期

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3. Gefitinib inhibits pregnane X receptor-induced cytochrome P450 3A4 gene expression in human hepatocytes [J] . Pondugula Satyanarayana R., Abbott Kodye L., Flannery Patrick C., Drug Metabolism Reviews . 2016,第1a4期

机译：吉非替尼抑制人肝细胞中妊娠X受体诱导的细胞色素P450 3A4基因表达
4. Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor [O] . Naoto Okada, Aki Murakami, Shiori Urushizaki, 2017

机译：未成熟橙（Aurantii fructus immaturus）和柑桔皮（Citri unshiupercarpium）的提取物通过上调孕烷X受体的表达来诱导P-糖蛋白和细胞色素P450 3A4的表达。
5. Byakangelicin induces cytochrome P450 3A4 expression via transactivation of pregnane X receptors in human hepatocytes [O] . Yang, Jian, Luan, Xiaofei, Gui, Haiyan, 2011

机译：Byakangelicelicin通过人肝细胞中孕烷X受体的反式激活诱导细胞色素P450 3A4表达

Extracts of Immature Orange (Aurantii fructus immaturus) and Citrus Unshiu Peel (Citri unshiu pericarpium) Induce P-Glycoprotein and Cytochrome P450 3A4 Expression via Upregulation of Pregnane X Receptor

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