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Solvent-resistant nanofiltration for product purification and catalyst recovery in Click chemistry reactions

机译:耐溶剂纳滤,用于产品纯化和点击化学反应中的催化剂回收

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摘要

The quickly developing field of "click" chemistry Would undoubtedly benefit from the availability of an easy and efficient technology for product purification to reduce the potential health risks associated with the presence of copper in the final product. Therefore. solvent-resistant nanofiltration (SRNF) membranes have been developed to selectively separate "clicked" polymers from the copper catalyst and solvent. By using these solvent-stable cross-linked polyimide membranes in diafiltration, up to 98% of the initially present copper could be removed through the membrane together with the DMF solvent, the polymer product being almost completely retained. This paper also presents the first SRNF application in which the catalyst permeates through the membrane and the reaction product is retained.
机译:快速发展的“点击”化学领域无疑将得益于简单易行的产品纯化技术,以减少与最终产品中存在的铜有关的潜在健康风险。因此。已经开发了耐溶剂纳米过滤(SRNF)膜,以选择性地从铜催化剂和溶剂中分离“点击”的聚合物。通过在渗滤中使用这些溶剂稳定的交联聚酰亚胺膜,可将高达98%的最初存在的铜与DMF溶剂一起通过该膜除去,几乎完全保留了聚合物产物。本文还介绍了第一个SRNF应用,其中催化剂渗透通过膜,并保留了反应产物。

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