Static mixers and multifunctional heat exchangers/reactors (MHE/R) are qualified as efficient receptacles for pro-cesses including physical or chemical transformations accompanied by heat transfer due to their high productivityand reduced energy expenditures. The present work reviews recent conceptual and technological innovations inpassive static mixers and continuous in-line reactors. Current industrial applications are discussed from a processintensification perspective, focusing on mixing and mass transfer performance. Typical experimental techniquesemployed to characterize and quantify the mixing process are explored. The work is complemented by a review ofmixing fundamentals, knowledge of which allows the development of theoretical models crucial for the analysis ofexperimental data, like the chemical probe mixing assessment method. Considering the development of continuousflow equipment in numerous processes, advances in this field will certainly be of increasing interest to the scientificand industrial communities.
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