Synthesis of glycosyl cyanamides from azides: application for the synthesis of N-​hydroxyguanidinoglycosides

摘要

A simple, concise and straightforward synthesis of a novel class of cyanamides and N-​hydroxyguanidines in carbohydrate scaffolds starting from the corresponding azides in moderate to good yields has been described. The protocol is simple and mild with broad substrate scope involving primary and secondary azides of a range of monosaccharides and disaccharides.