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Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation

机译：23 s rRNa的肽基转移酶中心的突变揭示了sparsomycin的作用位点，这是一种通用的翻译抑制剂

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Ghee T. Tan; Ra Deblasio; Er S. Mankin;
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年度 1996
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1. MUTATIONS IN THE PEPTIDYL TRANSFERASE CENTER OF 23 S RRNA REVEAL THE SITE OF ACTION OF SPARSOMYCIN, A UNIVERSAL INHIBITOR OF TRANSLATION [J] . Tan GT., Mankin AS., Deblasio A. Journal of Molecular Biology . 1996,第2期

机译：在23 S RRNA的肽基转移酶中心的突变表明，Sparsomycin是一种普遍的翻译抑制剂，其作用部位
2. Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center. [J] . Kloss P, Xiong L, Shinabarger DL, Journal of Molecular Biology . 1999,第1期

机译：23 S rRNA中的抗性突变确定了蛋白质合成抑制剂利奈唑胺在核糖体肽基转移酶中心的作用位点。
3. Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl ,transferase center of 23S-like rRNA within ribosome-tRNA complexes [J] . BO T. PORSE, STANISLAV V. KIRILLOV, MARIANA J.AWAYEZ Proceedings of the National Academy of Sciences of the United States of America . 1999,第16期

机译：抗肿瘤抗生素sparsomycin及其衍生物直接交联到核糖体-tRNA复合物中23S样rRNA的肽基转移酶中心的A2602
4. A Competitive Model Reaction for the ribosomal peptide bond formation catalyzed by peptidyl transferase [C] . Lin Cheng, Nian Hong, Xiang-qun Xu, International Conference on Frontiers of Manufacturing and Design Science . 2014

机译：用肽基转移酶催化的核糖体肽键形成的竞争模型反应
5. The effects of antibiotics and mutations on the decoding accuracy of translation and the revelation of A-site and P-site reciprocation. [D] . Maar, Dianna. 2007

机译：抗生素和突变对翻译解码精度以及A位和P位往复的启示的影响。
6. Direct crosslinking of the antitumor antibiotic sparsomycin and its derivatives to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes [O] . Bo T. Porse, Stanislav V. Kirillov, Mariana J. Awayez, 1999

机译：将抗肿瘤抗生素sparsomycin及其衍生物直接交联到核糖体-tRNA复合物中23S样rRNA的肽基转移酶中心的A2602
7. Direct crosslinking of the antitumor antibiotic sparsomycin, and its derivatives, to A2602 in the peptidyl transferase center of 23S-like rRNA within ribosome-tRNA complexes [O] . Porse, Bo T., Kirillov, Stanislav V., Awayez, Mariana J., 1999

机译：将抗肿瘤抗生素sparsomycin及其衍生物直接交联到核糖体-tRNA复合物中23S样rRNA的肽基转移酶中心的A2602

Mutations in the peptidyl transferase center of 23 S rRNA reveal the site of action of sparsomycin, a universal inhibitor of translation

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