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Phase I and Pharmacodynamic Trial of the DNA Methyltransferase Inhibitor Decitabine and Carboplatin in Solid Tumors

机译：实体瘤中DNa甲基转移酶抑制剂地西他滨和卡铂的I期和药效学试验

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Helen J. Mackay; Ian Judson; Jane A. Plumb; Carol Mccormick; Gordon Strathdee; Chooi Lee; Albert Setanoians; Chris Twelves; Stanley B. Kaye; Robert Brown;
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1. Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. [J] . Appleton K, Mackay HJ, Judson I, Journal of Clinical Oncology . 2007,第29期

机译：DNA甲基转移酶抑制剂地西他滨和卡铂在实体瘤中的I期和药效学试验。
2. A phase 1 trial of the oral DNA methyltransferase inhibitor CC‐486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors [J] . Gaillard Stéphanie L., Zahurak Marianna, Sharma Anup, Cancer: A Journal of the American Cancer Society . 2019,第16期

机译：口服DNA甲基转移酶抑制剂CC-486的第1期试验和在先进的实体瘤中的组蛋白脱乙酰酶抑制剂Romidepsin
3. A phase I trial of cisplatin plus decitabine, a new DNA-hypomethylating agent, in patients with advanced solid tumors and a follow-up early phase II evaluation in patients with inoperable non-small cell lung cancer. [J] . Schwartsmann G, Schunemann H, Gorini CN, Investigational new drugs. . 2000,第1期

机译：在晚期实体瘤患者中进行顺铂联合地西他滨（一种新的DNA次甲基化剂）的I期试验，并对无法手术的非小细胞肺癌患者进行早期II期随访评估。
4. Virtual screening of natural products as an inhibitor of DNA methyltransferase 1 enzyme for breast cancer disease [C] . Ina Nur Istiqomah, Ahmad Husein Alkaff, Mutiara Saragih Joint Conference on Chemistry . 2019

机译：天然产物的虚拟筛选作为DNA甲基转移酶1酶的抑制剂，用于乳腺癌疾病
5. The impact of DNA methyltransferase inhibitor treatment on tumor cell recognition by CD8+ T cells and their effector function. [D] . Paluch, Benjamin Edward. 2016

机译：DNA甲基转移酶抑制剂处理对CD8 + T细胞识别肿瘤细胞及其效应器功能的影响。
6. A randomised phase II trial of the DNA-hypomethylating agent 5-aza-2′-deoxycytidine (decitabine) in combination with carboplatin vs carboplatin alone in patients with recurrent partially platinum-sensitive ovarian cancer [O] . R M Glasspool, R Brown, M E Gore, 2014

机译：DNA-次甲基化剂5-氮杂2-脱氧胞苷（地西他滨）联合卡铂与单独卡铂联合用于部分复发性铂敏感性卵巢癌患者的随机II期试验
7. A phase 1 trial of the oral DNA methyltransferase inhibitor CC‐486 and the histone deacetylase inhibitor romidepsin in advanced solid tumors [O] . Stéphanie L. Gaillard, Marianna Zahurak, Anup Sharma, 2019

机译：口服DNA甲基转移酶抑制剂CC-486的第1期试验和在先进的实体瘤中的组蛋白脱乙酰酶抑制剂Romidepsin

Phase I and Pharmacodynamic Trial of the DNA Methyltransferase Inhibitor Decitabine and Carboplatin in Solid Tumors

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