Palladium-catalyzed oxidative direct C-H/C-H cross coupling of anilides with β-keto esters

摘要

A Pd(ii)-catalyzed oxidative direct C(sp2)-H/C(sp3)-H cross coupling of anilides with α-dicarbonyl compounds with Mn(OAc) 3·2H2O as the oxidant is reported and this protocol provides facile access to α-aryl malonates and β-keto esters in good yields and regioselectivity.