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Magnetic/plasmonic MnFe2O4/Au nanoparticles covered with lipid bilayers for applications in thermotherapy

机译:磁性/等离子MnFe2O4 / Au纳米颗粒覆盖有脂质双层,可用于热疗

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摘要

In this work, three different types of magnetic/plasmonic nanoparticles were prepared: core-shell nanoparticles with a manganese ferrite core and a gold shell; plasmonic gold nanoparticles decorated with magnetic nanoparticles of manganese ferrite; and magnetic nanoparticles of manganese ferrite decorated with plasmonic gold nanoparticles. The structural, spectroscopic and magnetic properties of these nanoparticles were evaluated. In order to further develop applications in cancer therapy, the prepared mixed nanoparticles were covered with a lipid bilayer. The local heating capability of these nanosystems was tested through the quenching of rhodamine fluorescence incorporated in the lipid layer.
机译:在这项工作中,制备了三种不同类型的磁性/等离子体纳米颗粒:具有锰铁氧体核和金壳的核-壳纳米颗粒;用锰铁氧体磁性纳米粒子修饰的等离子金纳米粒子;锰铁氧体的磁性纳米粒子,并带有等离激元金纳米粒子。评估了这些纳米颗粒的结构,光谱和磁性。为了进一步开发在癌症治疗中的应用,制备的混合纳米颗粒被脂质双层覆盖。这些纳米系统的局部加热能力是通过猝灭脂质层中掺入的若丹明荧光来测试的。

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