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The effect of silicone-hydrogel and conventional hydrogel contact lenses wear on the tear film: a comparison between de lenses

机译:有机硅-水凝胶和传统水凝胶隐形眼镜在泪膜上的磨损效果:镜片之间的比较

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摘要

Purpose: The aim of this study was to evaluate the effect of one conventionalhydrogel and four silicone-hydrogel contactlenses of 6-months daily wear on the quantityand stability of the tear film. The tests wereperformed with a group of patients with noprevious contact lenses experience beforeand after wear on 96 eyes.Methods: The contact lenses tested were:19 Galyfilcon A (Acuvue® Advance™), 15Balafilcon A (PureVision™), 20 LotrafilconA (Focus® Night & Day™), 14 Lotrafilcon B(O2Optix™) and 28 Etalfilcon A (Acuvue®).Each silicone-hydrogel contact lens was usedfor 1 month and the conventional hydrogelfor 15 days. Every patient used a different lens in each eye. Tear film stability was monitored by tear Break-up-time (BUT) and Non Invasive Break Up Time (NiBUT) and tear volume was measured by the Total Tear Meniscus Height and the Red Phenol Test.Results: The following tables summarizethe difference between the measurementsobtained in the first and in the last dayof wear of each contact lens brand andthe results were analyzed comparing theconventional hydrogel and the siliconehydrogelcontact lenses (Table 1, 2, and 3), the lenses belonging to the first generation of silicone-hydrogel contact lenses (table 4) and the lenses belonging to the second generation of silicone-hydrogel (Table 5). The significance (p value) of 0.05 is considered statistically significant.Conclusions: Although there are some differences between the lenses, there are nostatistically significant differences betweenthe lenses and measurements obtained before and after contact lenses wear on thetear film tests.
机译:目的:本研究的目的是评估一种常规水凝胶和四种有机硅-水凝胶隐形眼镜(每天佩戴6个月)对泪膜的数量和稳定性的影响。该测试是针对一组在戴过96眼之前和之后都没有接触镜的患者进行的。方法:测试的接触镜为:19 Galyfilcon A(Acuvue®Advance™),15Balafilcon A(PureVision™),20 LotrafilconA(Focus® Night&Day™),14片Lotrafilcon B(O2Optix™)和28片Etalfilcon A(Acuvue®)。每种有机硅-水凝胶隐形眼镜使用1个月,常规水凝胶使用15天。每个患者的每只眼睛都使用不同的镜片。通过撕裂时间(BUT)和非侵入性撕裂时间(NiBUT)监测泪膜的稳定性,并通过总撕裂半月板高度和红色苯酚测试测量泪液体积。结果:下表总结了撕裂时间的差异。每种隐形眼镜品牌在佩戴的第一天和最后一天获得的测量值,并对结果进行了比较,比较了传统水凝胶和有机硅水凝胶隐形眼镜(表1、2和3),它们属于第一代有机硅水凝胶隐形眼镜(表1、2和3)。表4)和属于第二代有机硅水凝胶的镜片(表5)。 0.05的显着性(p值)被认为具有统计学意义。结论:尽管镜片之间存在一些差异,但在泪膜测试中,隐形眼镜与隐形眼镜佩戴前后的测量结果之间,镜片之间没有统计学上的显着差异。

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