Symptoms and signs in rigid gas permeable lens wearers during adaptation period

摘要

Objectives: To evaluate neophyte contact lens wearers’ fitting to rigid gaspermeable (RGP) contact lenses in terms of wearing time, tear volume,stability, corneal staining, and subjective ratings, over a 1-month periodof time.Methods: Twenty-two young healthy subjects were enrolled for wearingRGP on a daily wear basis. The participants included in this study neverwore contact lenses and showed a value under 10 in McMonniesQuestionnaire. Contact Lens Dry Eye Questionnaire, Visual Analog Scales,Schirmer test, tear film break-up time (BUT), and corneal staining gradingwere performed. Follow-up visits were scheduled at 1, 7, 15, and 28 days.Results: Six subjects dropped out due to discomfort from the study before1 month (27% of discontinuation rate). Successful RGP wearers (16participants) achieved high levels of subjective vision and reported comfortscores of approximately 9 of 10 between 10 and 15 days. They reportedwearing their lenses for an average of 10.1262.43 hr after 1 month of wear.Conversely, unsuccessful wearers discontinued wearing the lenses after thefirst 10 to 15 days, showing comfort scores and wearing time significantlylower compared with the first day of wear. Schirmer test showed a signifi-cant increase at 10 days (P,0.001), and the BUT trends decreased after thefirst week of wear in unsuccessful group.Conclusions: Symptomatology related with dryness and discomfort, detectedduring the first 10 days of the adaptation, may help the clinician to predictthose participants who will potentially fail to adapt to RGP lens wear.