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Endocarditis lenta-patient survived septic shock: a case report

机译:患有心内膜炎的伦塔氏病患者在败血性休克中幸存:一例报告

摘要

Infective endocarditis is defi ned as an infection of the endocardial surface of the heart. Its intracardiac effects include severe valvular insuffi ciency, which may lead to intractable congestive heart failure and myocardialabscesses. This disease still carries a poor prognosis and a high mortality.A severe case of infective endocarditis with its complications is presented. A man with aortic prosthetic valve due to earlier aortic stenosis and corrected aortal coarctation and implanted pacemaker presentedwith prolonged unexplained fever, malaise, sweating, weight loss (15 kg/4 months) and lumbar pain. He was treated with broad-spectrum antibiotics prior IE diagnosis was considered. Echocardiogram showedaortic vegetations and possible periaortal abscess formation. Nonspecifi c infl ammation parameters were high positive. Cultures were constantly negative. His condition had deteriorated suddenly, and he had presentedwith worsening of cutaneous vasculitis, subacute glomerulonephritis and subsequent acute respiratory distress syndrome and septic shock. This patient survived with residual bilateral necrosis of the feet andtoxic peroneal paresis. At the end transthoracic echocardiogram showed enlarged heart chambers, LV mild dilated and concentric hypertrophy with ejection fraction about 40%, degenerative postinfl ammatory mitralvalve changes, mild mitral regurgitation and tricuspid regurgitation, postinfl ammatory aortic root fi brosis and moderate aortic valve stenosis (AVPG max 50,9 mmHg, AVPG mean 24 mmHg) with no pericardial effusion. Initial suspicion of Q fever was defi nitely excluded by serological testing showing nonspecifi c IgM positivity,probably rheumatoid factor related.
机译:感染性心内膜炎定义为心脏的心内膜表面感染。它的心内作用包括严重的瓣膜功能不全,可能导致顽固性充血性心力衰竭和心肌脓肿。该病预后差,病死率高。严重的感染性心内膜炎病例并发并发症。一个因主动脉瓣狭窄较早,主动脉缩窄而矫正并植入起搏器的主动脉人工瓣膜,伴有长期无法解释的发烧,不适,出汗,体重减轻(15千克/ 4个月)和腰痛。在考虑IE诊断之前,他曾接受过广谱抗生素治疗。超声心动图显示主动脉植被和可能的口周脓肿形成。非特异性炎症参数为高阳性。文化一直在消极。他的病情突然恶化,并伴有皮肤血管炎,亚急性肾小球肾炎和随后的急性呼吸窘迫综合征和败血性休克的恶化。该患者幸存,双足残留坏死,腓骨轻度麻痹。最终,经胸超声心动图显示心脏腔扩大,左心室轻度扩张和同心肥大,射血分数约40%,变性后的肺动脉二尖瓣改变,轻度二尖瓣反流和三尖瓣反流,后动脉血栓性主动脉根部纤维化和中度主动脉瓣狭窄(AVPG最大) 50,9 mmHg,AVPG平均为24 mmHg),无心包积液。血清学检查明确排除了最初对Q发热的怀疑,血清学检查显示IgM非特异性阳性,可能与类风湿因子有关。

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