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Spaces of convergence in a cancer clinical genomics trial: a survey examining genomic literacy among medical oncologists in British Columbia

机译:癌症临床基因组学试验中的融合空间:一项调查不列颠哥伦比亚省医学肿瘤学家基因组素养的调查

摘要

The emergence of big data in the network age has led to many innovative breakthroughs in all sectors of life. One significant breakthrough are the prominent applications of clinical genomics in developing personalized medicine. In this thesis I explore the technological diffusion of clinical genomics within the spaces of convergence of multidisciplinary medical stakeholders in the Personalized Onco-Genomics (POG) cancer clinical trial, I co-developed the concept of “Genomic literacy” by drawing upon three areas of scholarship: health communication, information communication technologies (ICTs), and science and technology. I gathered data using a survey and semi-structured interviews with medical oncologists and other scientists at. Using this data I examine how genomic literacy, attitudes, and experiences of the domain experts working with clinical genomics can determine the adoption of genomic technologies into clinical care. These spaces of convergence of multidisciplinary medical stakeholders also create a pedagogical space where the stakeholders come together. This bioclinical collective of stakeholders learn more about genomics through their communicative and discursive processes, as they co-construct knowledge and meaning with genomic information.
机译:网络时代大数据的出现导致生活各个领域的许多创新性突破。一项重大突破是临床基因组学在开发个性化医学方面的显着应用。在本论文中,我在个性化肿瘤基因组学(POG)癌症临床试验中探索了多学科医学利益相关者融合空间中临床基因组学的技术扩散,并通过借鉴以下三个方面共同开发了“基因组素养”概念。奖学金:健康传播,信息传播技术(ICT)和科学与技术。我通过对医学肿瘤学家和其他科学家的调查和半结构化访谈收集了数据。利用这些数据,我研究了基因组知识,态度和与临床基因组学相关的领域专家的经验如何确定基因组技术在临床护理中的采用。多学科医学利益相关者的这些融合空间也创建了利益相关者聚集在一起的教学空间。这个利益相关者的生物临床组织通过他们的交流和讨论过程,进一步了解基因组学,因为他们与基因组信息共同构建了知识和意义。

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    Ha Vu Tien Dung;

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