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Flexible conductive polymer electrodes for applications in tissue Electrical Impedance Scanning (EIS)

机译:用于组织电阻抗扫描(EIS)的柔性导电聚合物电极

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摘要

Electrical Impedance Scanning (EIS) is a potential alternative for breast cancer screening, and has been investigated as a breast cancer screening tool since the 1920s. However, it has not become a regular diagnostic tool due to limitations such as low spatial resolution, poor electrode design, and mechanical skin contact issues. In this thesis, we attempt to address these limitations through development and demonstration of a novel flexible conductive nanoparticle composite polymer (C-NCP) electrode array. The array is fabricated using a new multi-level soft lithography. The array is highly flexible, resulting in improved skin contact and easy conformability to curved surfaces. Flexible Ag/AgCl electrodes (average resistivity of 1.75x10-3 +/- 14.3% ohm-m) and Ag/graphene electrodes (average resistivity of 4.45x10-4 +/- 18.7% ohm-m) are fabricated and tested on a tissue phantom and animal flesh. The results are presented in Cole-Cole plot format for easy comparison between regular tissue and tissue with introduced anomalies.
机译:电阻抗扫描(EIS)是乳腺癌筛查的一种潜在替代方法,自1920年代以来就已作为乳腺癌筛查工具进行了研究。然而,由于诸如低空间分辨率,不良的电极设计和机械性皮肤接触问题之类的限制,它尚未成为常规的诊断工具。在本文中,我们试图通过开发和演示新型柔性导电纳米粒子复合聚合物(C-NCP)电极阵列来解决这些局限性。使用新的多层软光刻技术制造阵列。该阵列具有高度的柔韧性,可改善皮肤接触并易于适应曲面。制作了柔性Ag / AgCl电极(平均电阻率为1.75x10-3 +/- 14.3%ohm-m)和Ag /石墨烯电极(平均电阻率为4.45x10-4 +/- 18.7%ohm-m)并在组织体模和动物肉。结果以Cole-Cole绘图格式显示,可轻松比较常规组织和引入异常的组织。

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    Chung Daehan;

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  • 年度 2012
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